Molecular structure of 2-Hydroxytetrahydrofuran, CAS Number: 5371-52-8
2-Hydroxytetrahydrofuran (CAS 5371-52-8)
Alternate Names:
α-Hydroxytetrahydrofuran; Tetrahydro-2-furanol
CAS Number:
5371-52-8
Purity:
≥95%
Molecular Weight:
88.11
Molecular Formula:
C4H8O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2-Hydroxytetrahydrofuran (2-HTHF) is a compound useful in organic synthesis. It acts as a catalyst in the synthesis of drugs and polymers. It helps to speed up the reaction by increasing the rate of nucleophilic substitution. It also helps to increase the solubility of the reactants, thus allowing for a more efficient reaction.
2-Hydroxytetrahydrofuran (CAS 5371-52-8) References
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- Preferential metabolic activation of N-nitrosopiperidine as compared to its structural homologue N-nitrosopyrrolidine by rat nasal mucosal microsomes. | Wong, HL., et al. 2003. Chem Res Toxicol. 16: 1298-305. PMID: 14565771
- Novel dual inhibitors of calpain and lipid peroxidation. | Auvin, S., et al. 2004. Bioorg Med Chem Lett. 14: 3825-8. PMID: 15203170
- Metabolism and cometabolism of cyclic ethers by a filamentous fungus, a Graphium sp. | Skinner, K., et al. 2009. Appl Environ Microbiol. 75: 5514-22. PMID: 19581469
- Recombinant expression, purification, and characterization of ThmD, the oxidoreductase component of tetrahydrofuran monooxygenase. | Oppenheimer, M., et al. 2010. Arch Biochem Biophys. 496: 123-31. PMID: 20159007
- Isolation of a 2-hydroxytetrahydrofuran complex from copper-promoted hydroxylation of THF. | Halvagar, MR. and Tolman, WB. 2013. Inorg Chem. 52: 8306-8. PMID: 23886308
- Oxidation of the cyclic ethers 1,4-dioxane and tetrahydrofuran by a monooxygenase in two Pseudonocardia species. | Sales, CM., et al. 2013. Appl Environ Microbiol. 79: 7702-8. PMID: 24096414
- Biodegradation of Tetrahydrofuran by the Newly Isolated Filamentous Fungus Pseudallescheria boydii ZM01. | Ren, H., et al. 2020. Microorganisms. 8: PMID: 32764240
- Atmospheric Ring-Closure and Dehydration Reactions of 1,4-Hydroxycarbonyls in the Gas Phase: The Impact of Catalysts. | Arathala, P., et al. 2021. J Phys Chem A. 125: 5963-5975. PMID: 34191509
- A Multicomponent THF Hydroxylase Initiates Tetrahydrofuran Degradation in Cupriavidus metallidurans ZM02. | Ren, H., et al. 2022. Appl Environ Microbiol. 88: e0188021. PMID: 35108100
- Diastereoselective, Catalytic Access to Cross-Aldol Products Directly from Esters and Lactones. | Moreno González, A., et al. 2022. Angew Chem Int Ed Engl. 61: e202209584. PMID: 35916601
- High pressure liquid chromatographic assay for alpha hydroxylation of N-nitrosopyrrolidine by isolated rat liver microsomes. | Chen, CB., et al. 1978. Cancer Res. 38: 3812-6. PMID: 698939
- Lactols in hydrolysates of DNA treated with alpha-acetoxy-N-nitrosopyrrolidine or crotonaldehyde. | Wang, M., et al. 1998. Chem Res Toxicol. 11: 1567-73. PMID: 9860502
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Hydroxytetrahydrofuran, 250 mg | sc-209203 | 250 mg | $316.00 | |||
2-Hydroxytetrahydrofuran, 1 g | sc-209203A | 1 g | $500.00 |