Date published: 2026-4-30

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2-Bromo-N-[3-(trifluoromethyl)phenyl]acetamide (CAS 25625-57-4)

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Alternate Names:
2-Bromo-m-trifluoromethylacetanilide; 2-Bromo-α,α,α-trifluoro-m-acetotoluidide; m-Trifluoromethyl-α-bromoacetanilide
CAS Number:
25625-57-4
Molecular Weight:
282.06
Molecular Formula:
C9H7BrF3NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Bromo-N-[3-(trifluoromethyl)phenyl]acetamide, also referred to as 2-BTFPA, is an extensively utilized bromoacetamide compound with diverse applications in scientific research. Its remarkable versatility makes it valuable in the synthesis of various organic compounds and as a catalyst for numerous reactions. In the field of organic synthesis, 2-Bromo-N-[3-(trifluoromethyl)phenyl]acetamide plays a role, facilitating the production of an extensive range of compounds.Additionally, it acts as a catalyst for synthesizing diverse organic compounds including polymer materials and other organic substances. It involves the formation of a bromonium ion intermediate. Subsequently, this intermediate is susceptible to attack by a nucleophile, such as a carboxylic acid, resulting in the desired product. Furthermore, 2-Bromo-N-[3-(trifluoromethyl)phenyl]acetamide demonstrates excellent catalytic properties for oxidizing alcohols into aldehydes and ketones.


2-Bromo-N-[3-(trifluoromethyl)phenyl]acetamide (CAS 25625-57-4) References

  1. Synthesis and cytotoxicity of thieno[2,3-b]quinoline-2-carboxamide and cycloalkyl[b]thieno[3,2-e]pyridine-2-carboxamide derivatives.  |  Leung, E., et al. 2016. Bioorg Med Chem. 24: 1142-54. PMID: 26853836
  2. Development of Small Molecules with a Noncanonical Binding Mode to HIV-1 Trans Activation Response (TAR) RNA.  |  Abulwerdi, FA., et al. 2016. J Med Chem. 59: 11148-11160. PMID: 28002966
  3. Synthesis and Anti-Trypanosoma cruzi Biological Evaluation of Novel 2-Nitropyrrole Derivatives.  |  Mathias, F., et al. 2022. Molecules. 27: PMID: 35408570

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Bromo-N-[3-(trifluoromethyl)phenyl]acetamide, 500 mg

sc-307185
500 mg
$284.00