2-Bromo-1-indanol (CAS 5400-80-6)

2-Bromo-1-indanol is a brominated organic compound that is a derivative of indanol, characterized by a bromine atom substituted at the second position on the indanol structure. This compound is particularly valuable in the realm of organic synthesis, where it serves as an intermediate for the preparation of various chemically and biologically active molecules. The primary mechanism of action of 2-Bromo-1-indanol in research involves its role in facilitating nucleophilic substitution reactions due to the presence of the bromine atom. Bromine is a good leaving group, making this compound a useful precursor in reactions aiming to introduce new functional groups in place of the bromine atom. This can include the synthesis of more complex heterocyclic structures where the indanol core serves as a versatile scaffold. In the realm of synthetic organic chemistry, 2-Bromo-1-indanol is utilized to explore the synthesis of new indole derivatives. The indole structure is significant in many natural products and active pharmaceutical ingredients. By modifying the indanol scaffold, researchers can derive new compounds with potential activities, investigating how these modifications influence biological activity. Moreover, 2-Bromo-1-indanol is used in materials science, particularly in the synthesis of optoelectronic materials. Its unique structure can influence the electronic properties of polymers and small molecules when incorporated into these materials. Research in this area focuses on how the brominated indanol derivative can affect light absorption and emission properties, which are critical for applications in light-emitting diodes and photovoltaic cells.