Date published: 2025-9-5

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2-Azidoethanol (CAS 1517-05-1)

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Alternate Names:
2-Azidoethanol is also known as 2-Hydroxyethyl Azide.
Application:
2-Azidoethanol is a reagent used in glycosylation and 2′-deoxy-ethynyluridine (EdU) blocker in nuclear DNA.
CAS Number:
1517-05-1
Molecular Weight:
87.08
Molecular Formula:
C2H5N3O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Azidoethanol is a reagent involved in the glycosylation of mono- and polysaccharides. In addition, it is used to block 2′-deoxy-ethylnyluridine in nuclear DNA. This action allows 2-Azidoethanol to effectively prevent cross-reactivity with other antibodies.


2-Azidoethanol (CAS 1517-05-1) References

  1. Regiochemical studies of the ring expansion reactions of hydroxy azides with cyclic ketones.  |  Smith, BT., et al. 2000. J Org Chem. 65: 3771-4. PMID: 10864763
  2. Glycosaminoglycan mimetic biomaterials. 4. Synthesis of sulfated lactose-based glycopolymers that exhibit anticoagulant activity.  |  Sun, XL., et al. 2002. Biomacromolecules. 3: 1065-70. PMID: 12217054
  3. A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems.  |  Agard, NJ., et al. 2004. J Am Chem Soc. 126: 15046-7. PMID: 15547999
  4. Mutagenic activity of 6-azido deoxyhexoses and azido alcohols in Salmonella typhimurium and its inhibition by a structure-similar carbon source in the medium.  |  Juricek, M., et al. 1991. Mutat Res. 251: 13-20. PMID: 1944370
  5. Cooperative binding of bifunctionalized and click-synthesized silver nanoparticles for colorimetric co(2+) sensing.  |  Yao, Y., et al. 2010. ACS Appl Mater Interfaces. 2: 684-90. PMID: 20356269
  6. Ultrasonic assisted Fischer glycosylation: generating diversity for glycochemistry.  |  Shaikh, N., et al. 2011. Mol Divers. 15: 341-5. PMID: 20931279
  7. Synthesis of a fluorogenic cyclooctyne activated by Cu-free click chemistry.  |  Jewett, JC. and Bertozzi, CR. 2011. Org Lett. 13: 5937-9. PMID: 22029411
  8. Protection/Deprotection of surface activity and its applications in the controlled release of liposomal contents.  |  Li, X. and Zhao, Y. 2012. Langmuir. 28: 4152-9. PMID: 22303995
  9. Most anti-BrdU antibodies react with 2'-deoxy-5-ethynyluridine -- the method for the effective suppression of this cross-reactivity.  |  Liboska, R., et al. 2012. PLoS One. 7: e51679. PMID: 23272138
  10. Site-specific peptide and protein immobilization on surface plasmon resonance chips via strain-promoted cycloaddition.  |  Wammes, AE., et al. 2013. Lab Chip. 13: 1863-7. PMID: 23552823
  11. Accurate prediction of enthalpies of formation of organic azides by combining G4 theory calculations with an isodesmic reaction scheme.  |  Dorofeeva, OV., et al. 2013. J Phys Chem A. 117: 6835-45. PMID: 23834503
  12. Fully automated radiosynthesis of [1-(2-[18 F]fluoroethyl),1H[1,2,3]triazole 4-ethylene] triphenylphosphonium bromide as a potential positron emission tomography tracer for imaging apoptosis.  |  Haslop, A., et al. 2013. J Labelled Comp Radiopharm. 56: 313-6. PMID: 24285410
  13. Autocatalytic Cycles in a Copper-Catalyzed Azide-Alkyne Cycloaddition Reaction.  |  Semenov, SN., et al. 2018. J Am Chem Soc. 140: 10221-10232. PMID: 30035540
  14. Intumescent Phosphorus and Triazole-Based Flame-Retardant Polyurethane Foams from Castor Oil.  |  Sykam, K., et al. 2019. ACS Omega. 4: 1086-1094. PMID: 31459384

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Azidoethanol, 500 mg

sc-503216D
500 mg
$194.00

2-Azidoethanol, 1 g

sc-503216
1 g
$245.00

2-Azidoethanol, 2 g

sc-503216A
2 g
$347.00

2-Azidoethanol, 5 g

sc-503216B
5 g
$605.00

2-Azidoethanol, 10 g

sc-503216C
10 g
$959.00