2-Aminopurine (CAS 452-06-2)
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2-Aminopurine is an analog of adenine, one of the four nucleobases found in DNA and RNA, distinguished by the substitution of an amino group at the position where adenine has an NH2 group. This modification imbues 2-aminopurine with unique fluorescent properties and the ability to act as a sensitive probe for monitoring DNA and RNA processes in vitro. In the realm of biochemical research, 2-aminopurine serves as a pivotal tool for investigating the mechanisms of nucleic acid folding, replication, and transcription, as well as protein-nucleic acid interactions. Its fluorescence increases significantly upon incorporation into DNA or RNA, making it an invaluable reporter for studying the dynamics of nucleic acid conformations and the effects of mutations on the stability and function of nucleic acid structures. Furthermore, 2-aminopurine′s ability to mimic adenine allows for the exploration of enzyme-substrate interactions and the fidelity of nucleic acid polymerases, thus enhancing our understanding of the molecular underpinnings of genetic information processing and the intricate web of life at the molecular level.
2-Aminopurine (CAS 452-06-2) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Aminopurine, 100 mg | sc-287828 | 100 mg | $118.00 | |||
2-Aminopurine, 250 mg | sc-287828A | 250 mg | $185.00 |