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2-Aminoacridone (CAS 27918-14-5)

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Alternate Names:
2-Amino-9(10H)-acridinone; 2-amino-10H-acridin-9-one; AMAC
Application:
2-Aminoacridone is a highly fluorescent aromatic
CAS Number:
27918-14-5
Purity:
≥98%
Molecular Weight:
210.23
Molecular Formula:
C13H10N2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Aminoacridone (2-AAC) is a synthetic compound widely employed in scientific research for its versatile applications. It possesses distinctive characteristics, including its capacity to adhere to proteins and interact with various molecules. The field of biochemistry and physiology has extensively investigated 2-Aminoacridone, uncovering its synthesis method, mechanism of action, biochemical and physiological effects, as well as its advantages and limitations for laboratory experiments. The interaction between 2-Aminoacridone and proteins occurs through the establishment of hydrogen bonds with the amino acid side chains within the protein. This binding process yields a stable complex between the protein and the 2-Aminoacridone molecule. Consequently, this complex has the potential to interact with other molecules, including enzymes, thereby influencing their activity.


2-Aminoacridone (CAS 27918-14-5) References

  1. Ultrasensitive capillary electrophoresis of sulfated disaccharides in chondroitin/dermatan sulfates by laser-induced fluorescence after derivatization with 2-aminoacridone.  |  Lamari, F., et al. 1999. J Chromatogr B Biomed Sci Appl. 730: 129-33. PMID: 10437680
  2. Electrospray mass spectrometry and fragmentation of N-linked carbohydrates derivatized at the reducing terminus.  |  Harvey, DJ. 2000. J Am Soc Mass Spectrom. 11: 900-15. PMID: 11014452
  3. Large-scale preparation, purification, and characterization of hyaluronan oligosaccharides from 4-mers to 52-mers.  |  Tawada, A., et al. 2002. Glycobiology. 12: 421-6. PMID: 12122023
  4. Peptide substrate for caspase-3 with 2-aminoacridone as reporting group.  |  Lozanov, V., et al. 2009. Amino Acids. 36: 581-6. PMID: 18597040
  5. Mild and selective labeling of malondialdehyde with 2-aminoacridone: assessment of urinary malondialdehyde levels.  |  Giera, M., et al. 2011. Analyst. 136: 2763-9. PMID: 21611666
  6. Capillary electrophoresis separation of human milk neutral and acidic oligosaccharides derivatized with 2-aminoacridone.  |  Galeotti, F., et al. 2014. Electrophoresis. 35: 811-8. PMID: 24338619
  7. Analysis of glycosaminoglycan-derived, precolumn, 2-aminoacridone-labeled disaccharides with LC-fluorescence and LC-MS detection.  |  Volpi, N., et al. 2014. Nat Protoc. 9: 541-58. PMID: 24504479
  8. The Synthesis of L-Alanyl and β-Alanyl Derivatives of 2-Aminoacridone and Their Application in the Detection of Clinically-Important Microorganisms.  |  Cellier, M., et al. 2016. PLoS One. 11: e0158378. PMID: 27391894
  9. The analysis of fluorophore-labeled glycans by high-resolution polyacrylamide gel electrophoresis.  |  Jackson, P. 1994. Anal Biochem. 216: 243-52. PMID: 8179179
  10. The analysis of fluorophore-labeled carbohydrates by polyacrylamide gel electrophoresis.  |  Jackson, P. 1996. Mol Biotechnol. 5: 101-23. PMID: 8734424
  11. Fingerprinting of glycans as their 2-aminoacridone derivatives by capillary electrophoresis and laser-induced fluorescence.  |  Harland, GB., et al. 1996. Electrophoresis. 17: 406-11. PMID: 8900951
  12. High-performance liquid chromatographic analysis of complex N-linked glycans derivatized with 2-aminoacridone.  |  Okafo, G., et al. 1997. Anal Chem. 69: 4985-93. PMID: 9414612
  13. Profiling of 2-aminoacridone derivatised glycans by electrospray ionization mass spectrometry.  |  Charlwood, J., et al. 1999. Rapid Commun Mass Spectrom. 13: 107-12. PMID: 9951411

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Aminoacridone, 25 mg

sc-213751
25 mg
$99.00

2-Aminoacridone, 100 mg

sc-213751A
100 mg
$267.00