Date published: 2025-10-18

1-800-457-3801

SCBT Portrait Logo
Seach Input

2-Amino-3-methoxybenzoic acid (CAS 3177-80-8)

0.0(0)
Write a reviewAsk a question

Alternate Names:
3-Methoxyanthranilic acid
CAS Number:
3177-80-8
Molecular Weight:
167.16
Molecular Formula:
C8H9NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

2-Amino-3-methoxybenzoic acid functions as a chemical intermediate in research and development applications. It is involved in the synthesis of various organic compounds and can serve as a building block for the preparation of more complex molecules. At the molecular level, 2-Amino-3-methoxybenzoic acid can participate in nucleophilic aromatic substitution reactions, allowing for the introduction of specific functional groups into the molecular structure. 2-Amino-3-Methoxybenzoic Acid′s mechanism of action involves its ability to undergo chemical reactions with other compounds, leading to the formation of new chemical entities with distinct properties. In experimental applications, 2-Amino-3-methoxybenzoic acid can contribute to the diversification of chemical libraries and the exploration of structure-activity relationships in organic synthesis. Its role in the modification of molecular structures may be useful for the investigation of chemical reactivity and the development of novel compounds with potential applications in various fields.


2-Amino-3-methoxybenzoic acid (CAS 3177-80-8) References

  1. Synthesis and pharmacological testing of 1,2,3,4,10,14b-hexahydro-6-methoxy-2-methyldibenzo[c,f]pyrazino[1,2-a]azepin and its enantiomers in comparison with the two antidepressants mianserin and mirtazapine.  |  Wikström, HV., et al. 2002. J Med Chem. 45: 3280-5. PMID: 12109911
  2. Substituent effects on the reactivity of benzo-1,2-dithiolan-3-one 1-oxides and their possible application to the synthesis of DNA-targeting drugs.  |  Sawwan, N., et al. 2005. J Org Chem. 70: 6968-71. PMID: 16095328
  3. Benzyne click chemistry with in situ generated aromatic azides.  |  Zhang, F. and Moses, JE. 2009. Org Lett. 11: 1587-90. PMID: 19267454
  4. The benzodiazepine-like natural product tilivalline is produced by the entomopathogenic bacterium Xenorhabdus eapokensis.  |  Wolff, H. and Bode, HB. 2018. PLoS One. 13: e0194297. PMID: 29596433
  5. Discovery and Optimization of 2-Amino-4-methylquinazoline Derivatives as Highly Potent Phosphatidylinositol 3-Kinase Inhibitors for Cancer Treatment.  |  Lin, S., et al. 2018. J Med Chem. 61: 6087-6109. PMID: 29927604
  6. A structural-chemical explanation of fungal laccase activity.  |  Mehra, R., et al. 2018. Sci Rep. 8: 17285. PMID: 30470810
  7. Novel textile dye obtained through transformation of 2-amino-3-methoxybenzoic acid by free and immobilised laccase from a Pleurotus ostreatus strain.  |  Wlizło, K., et al. 2020. Enzyme Microb Technol. 132: 109398. PMID: 31731976
  8. 18F-labeled radiotracers for in vivo imaging of DREADD with positron emission tomography.  |  Hu, F., et al. 2021. Eur J Med Chem. 213: 113047. PMID: 33280897
  9. Novel sulphonamide-bearing methoxyquinazolinone derivatives as anticancer and apoptosis inducers: synthesis, biological evaluation and in silico studies.  |  Alqahtani, AS., et al. 2022. J Enzyme Inhib Med Chem. 37: 86-99. PMID: 34894963
  10. Genome, transcriptome, and metabolome analyses provide new insights into the resource development in an edible fungus Dictyophora indusiata.  |  Duan, M., et al. 2023. Front Microbiol. 14: 1137159. PMID: 36846778
  11. Synthesis and recognition properties of α-D-glucose-based fluorescent crown ethers incorporating an acridine unit  |  Zsolt Rapi, Péter Bakó, György Keglevich, Péter Baranyai, Miklós Kubinyi & Olívia Varga. 2014. Journal of Inclusion Phenomena and Macrocyclic Chemistry. 80: 253–261.
  12. Synthesis 4-[2-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-ethyl]-benzenesulfonamides with subnanomolar carbonic anhydrase II and XII inhibitory properties  |  Murat Bozdag a, Ahmed M. Alafeefy b, Fabrizio Carta a, Mariangela Ceruso a, Abdul-Malek S. Al-Tamimi c, Abdulla A. Al-Kahtani c d, Fatmah A.S. Alasmary d, Claudiu T. Supuran a. 2016. Bioorganic & Medicinal Chemistry. 24: 4100-4107.
  13. Dynamic changes in the chemical composition and metabolite profiles of drumstick (Moringa oleifera Lam.) leaf flour during fermentation  |  Honghui Shi a, Endian Yang c d e, Heyue Yang c d e, Xiaoling Huang c d e, Mengxia Zheng e, Xiaoyang Chen b c d e, Junjie Zhang c d e. 2022. LWT. 155.
  14. Effects of commercial sterilization on non-ginsenoside functional components in fresh ginseng pulps using widely targeted metabolomics  |  Junshun Zhang a, Zhiyi Ai a, Jian Wu b, Sitong Liu a, Yue Hu a, Yongzhe Liu a, Ping Tang a, Linlin Cui a, Xia Li a c, Chunhong Piao a c, Bo Nan a c, Yuhua Wang a c d e. 2023. LWT. 183.
  15. Chapter 6 - Benzene fused pyrimidine-based derivatives and their biological properties  |  Jeremy M. Kelm ∗ a, Hariprasad Aruri ∗ a, Prasanth R. Nyalapatla b, Navnath S. Gavande a. 20223. Fused Pyrimidine-Based Drug Discovery. 165-191.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Amino-3-methoxybenzoic acid, 1 g

sc-470172
1 g
$46.00