Date published: 2025-10-11

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2,4,6-Trichloropyrimidine (CAS 3764-01-0)

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Alternate Names:
Pyrimidine, 2,4,6-trichloro-
Application:
2,4,6-Trichloropyrimidine is 2,4,6-Trichloropyrimidine is a fungitoxic substance.
CAS Number:
3764-01-0
Molecular Weight:
183.42
Molecular Formula:
C4HCl3N2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,4,6-Trichloropyrimidine (2,4,6-TCP) is a halogenated organic compound that has found extensive applications in scientific research. Its significance lies in serving as a vital intermediate in the synthesis of pyrimidine derivatives. The versatile nature of 2,4,6-Trichloropyrimidine has led to its application in various scientific research endeavors. In vitro studies have focused on its inhibitory effects on the growth of specific bacterial strains. The precise mechanism of action underlying 2,4,6-Trichloropyrimidine′s effects is not yet fully elucidated. However, it is believed to exert its influence by impeding the growth of fungi and bacteria. Specifically, it is hypothesized to hinder the activity of enzymes involved in nucleic acid and protein synthesis.


2,4,6-Trichloropyrimidine (CAS 3764-01-0) References

  1. Synthesis and PI3 Kinase Inhibition Activity of Some Novel Trisubstituted Morpholinopyrimidines.  |  Wright, EW., et al. 2018. Molecules. 23: PMID: 29996482
  2. Durable Antipilling Modification of Cotton Fabric with Chloropyrimidine Compounds.  |  Dong, X., et al. 2019. Polymers (Basel). 11: PMID: 31623203
  3. Discovery of Aminopyrazole Derivatives as Potent Inhibitors of Wild-Type and Gatekeeper Mutant FGFR2 and 3.  |  Brawn, RA., et al. 2021. ACS Med Chem Lett. 12: 93-98. PMID: 33488969
  4. The development of an effective synthetic route of rilpivirine.  |  Zhang, T., et al. 2021. BMC Chem. 15: 22. PMID: 33810807
  5. Design, Synthesis, and Antitumor Activity of Olmutinib Derivatives Containing Acrylamide Moiety.  |  Hu, X., et al. 2021. Molecules. 26: PMID: 34065165
  6. Synthetic Strategies of Pyrimidine-Based Scaffolds as Aurora Kinase and Polo-like Kinase Inhibitors.  |  Jadhav, M., et al. 2021. Molecules. 26: PMID: 34500603
  7. Discovery of Potential Neuroprotective Agents against Paclitaxel-Induced Peripheral Neuropathy.  |  Chen, YF., et al. 2022. J Med Chem. 65: 4767-4782. PMID: 35234475
  8. Excited-State Intramolecular Proton Transfer in 2-(2'-Hydroxyphenyl)pyrimidines: Synthesis, Optical Properties, and Theoretical Studies.  |  Plaza-Pedroche, R., et al. 2022. ACS Appl Mater Interfaces. 14: 24964-24979. PMID: 35579566
  9. Antibody dual-functionalisation enabled through a modular divinylpyrimidine disulfide rebridging strategy.  |  Hanby, AR., et al. 2022. Chem Commun (Camb). 58: 9401-9404. PMID: 35912884
  10. Anti-Wrinkle and Dyeing Properties of Silk Fabric Finished with 2,4,6-Trichloropyrimidine.  |  Li, M., et al. 2022. Polymers (Basel). 14: PMID: 36015590
  11. Developments of pyridodipyrimidine heterocycles and their biological activities.  |  Hammouda, MM., et al. 2023. Mol Divers. 1-38. PMID: 36840839
  12. Synthesis of Phosphorus(V)-Substituted Six-Membered N-Heterocycles: Recent Progress and Challenges.  |  Volkova, Y. and Zavarzin, I. 2023. Molecules. 28: PMID: 36985443

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,4,6-Trichloropyrimidine, 25 g

sc-254350
25 g
$63.00