2-(3-Aminopropylamino)ethanol (CAS 4461-39-6)
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2-(3-Aminopropylamino)ethanol, an organic compound belonging to the amine family, serves as a versatile building block for various chemical compounds. This colorless liquid, with a faint odor, finds primary utility as a reagent in diverse laboratory experiments. Its applications in scientific research are multifaceted, encompassing the synthesis of different chemical compounds and extensive studies on its mechanism of action. The significance of 2-(3-Aminopropylamino)ethanol in scientific research extends to various domains. It serves as a reagent in synthesizing polymers, contributing to the production of pharmaceuticals, peptides, proteins, organic dyes, and pigments. Furthermore, this compound has played a vital role in studying enzyme kinetics and elucidating the mechanism of action of specific drugs. Although the precise mechanism of action of 2-(3-Aminopropylamino)ethanol remains elusive, it is believed to involve the formation of a hydrogen bond between this molecule and the target molecule. This hydrogen bond facilitates the interaction between 2-(3-Aminopropylamino)ethanol and the target molecule, ultimately impacting the structure and function of the target molecule.
2-(3-Aminopropylamino)ethanol (CAS 4461-39-6) References
- Structure-activity analysis of the potentiation by aminothiols of the chromosome-damaging effect of bleomycin in G0 human lymphocytes. | Hoffmann, GR., et al. 2001. Environ Mol Mutagen. 37: 117-27. PMID: 11246218
- Verification of exposure to organophosphates: Generic mass spectrometric method for detection of human butyrylcholinesterase adducts. | Noort, D., et al. 2006. Anal Chem. 78: 6640-4. PMID: 16970345
- Long-term suppression of ocular neovascularization by intraocular injection of biodegradable polymeric particles containing a serpin-derived peptide. | Shmueli, RB., et al. 2013. Biomaterials. 34: 7544-51. PMID: 23849876
- Differential polymer structure tunes mechanism of cellular uptake and transfection routes of poly(β-amino ester) polyplexes in human breast cancer cells. | Kim, J., et al. 2014. Bioconjug Chem. 25: 43-51. PMID: 24320687
- Continuous microfluidic assembly of biodegradable poly(beta-amino ester)/DNA nanoparticles for enhanced gene delivery. | Wilson, DR., et al. 2017. J Biomed Mater Res A. 105: 1813-1825. PMID: 28177587
- Polymeric nanoparticles as cancer-specific DNA delivery vectors to human hepatocellular carcinoma. | Zamboni, CG., et al. 2017. J Control Release. 263: 18-28. PMID: 28351668
- Differentially Branched Ester Amine Quadpolymers with Amphiphilic and pH-Sensitive Properties for Efficient Plasmid DNA Delivery. | Wilson, DR., et al. 2019. Mol Pharm. 16: 655-668. PMID: 30615464
- High-throughput evaluation of polymeric nanoparticles for tissue-targeted gene expression using barcoded plasmid DNA. | Kim, J., et al. 2021. J Control Release. 337: 105-116. PMID: 34097924
- Poly(beta-amino ester) nanoparticles enable tumor-specific TRAIL secretion and a bystander effect to treat liver cancer. | Vaughan, HJ., et al. 2021. Mol Ther Oncolytics. 21: 377-388. PMID: 34189258
- E7-Targeted Nanotherapeutics for Key HPV Afflicted Cervical Lesions by Employing CRISPR/Cas9 and Poly (Beta-Amino Ester). | Xiong, J., et al. 2021. Int J Nanomedicine. 16: 7609-7622. PMID: 34819726
- Novel elimination reaction of a hydroxyethyl group in a manganese complex. Formation of a binuclear manganese(II) complex with a Robson-type macrocyclic ligand | Mikuriya, M., Nakadera, K., & Tokii, T. 1992. Inorganica chimica acta. 194(2): 129-131.
- Immobilization of aminothiols on poly(oxyethylene H-phosphonate)s and poly(oxyethylene phosphate)s-An approach to polymeric protective agents for radiotherapy of cancer | Troev, K., Tsatcheva, I., Koseva, N., Georgieva, R., & Gitsov, I. 2007. Journal of Polymer Science Part A: Polymer Chemistry. 45(7): 1349-1363.
- Halide Ion Mediated Aldehyde-Amine Condensation Leading to Schiff–base and Cyclized Non-Schiff–base Ligand Complexes of CdII: A Combined Experimental and Theoretical Investigation | Purkait, S., Chakraborty, P., Bauzá, A., Frontera, A., Massera, C., & Das, D. 2016. ChemistrySelect. 1(15): 4539-4549.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-(3-Aminopropylamino)ethanol, 5 g | sc-251663 | 5 g | $107.00 |