2,3:5,6-Di-O-isopropylidene-α-D-mannofuranose (CAS 14131-84-1)

2,3:5,6-Di-O-isopropylidene-α-D-mannofuranose is a key compound in carbohydrate chemistry research, serving as a building block for the synthesis of various carbohydrate derivatives and mimetics. Its mechanism of action is rooted in its chemical structure, featuring isopropylidene groups protecting the 2,3 and 5,6 hydroxyl positions of the mannofuranose ring. This protective strategy enhances the stability of the compound and allows for selective functionalization at other hydroxyl groups. Researchers utilize 2,3:5,6-Di-O-isopropylidene-α-D-mannofuranose in the synthesis of complex carbohydrate structures, including glycosides, glycoconjugates, and oligosaccharides. By employing chemical transformations such as glycosylation, glycosidation, and glycosyl transfer reactions, scientists can access diverse glycan motifs for studying carbohydrate-protein interactions, cell recognition processes, and carbohydrate-mediated signaling pathways. Additionally, this compound serves as a precursor for the preparation of carbohydrate-based materials and biomimetic systems with applications in biotechnology, materials science, and drug delivery. Its compatibility with various synthetic methodologies and ease of manipulation make it a valuable tool for elucidating the roles of carbohydrates in biological systems and developing carbohydrate-based diagnostics. Through its versatile applications in carbohydrate research, 2,3:5,6-Di-O-isopropylidene-α-D-mannofuranose contributes to advancements in understanding carbohydrate structure-function relationships and exploiting their potential in diverse research fields.