Date published: 2026-2-12

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15-OxoEDE (CAS 105835-44-7)

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Alternate Names:
15-KEDE
Application:
15-OxoEDE is an oxidative derivative of 15-HEDE that acts as a less potent inhibitor of 5-LO
CAS Number:
105835-44-7
Molecular Weight:
322.5
Molecular Formula:
C20H34O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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15-OxoEDE, identified by the CAS number 105835-44-7, is a specialized eicosanoid derivative known for its role as an oxidative metabolite of dihomo-γ-linolenic acid (DGLA). This compound is particularly noteworthy for the keto group introduced at the 15th carbon, which distinguishes it from its parent hydroxyeicosanoids. In biochemical research, 15-OxoEDE has been extensively studied for its influence on cellular mechanisms involving the regulation of inflammatory mediators and its interaction with specific signaling pathways. This compound is known to affect the expression of genes related to cellular stress responses and has been a focus in studies examining the dynamics of lipid peroxidation products in cellular environments. The action of 15-OxoEDE in research settings has provided insights into its role in modulating receptor-mediated signal transduction pathways and its effects on transcription factors that regulate inflammatory processes. Its utility in research extends to exploring how oxidative metabolites of fatty acids can influence cellular behavior and signaling, providing a deeper understanding of the biochemical landscape within cells that responds to oxidative stress. By studying 15-OxoEDE, researchers are able to gain a better understanding of the complex interactions between lipid metabolism and cellular regulatory mechanisms, which are critical for maintaining cellular homeostasis under various physiological conditions.


15-OxoEDE (CAS 105835-44-7) References

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  3. Enzymatic and Non-Enzymatic Mechanisms Contribute to Lipid Oxidation During Seed Aging.  |  Oenel, A., et al. 2017. Plant Cell Physiol. 58: 925-933. PMID: 28371855
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  5. Simultaneous Quantitation of Lipid Biomarkers for Inflammatory Bowel Disease Using LC-MS/MS.  |  Chhonker, YS., et al. 2021. Metabolites. 11: PMID: 33673198
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

15-OxoEDE, 25 µg

sc-205026
25 µg
$68.00

15-OxoEDE, 50 µg

sc-205026A
50 µg
$129.00