13(S)-HODE-d4 (CAS 139408-39-2)

13(S)-HODE-d4, cataloged under CAS number 139408-39-2, is a deuterated form of 13(S)-hydroxyoctadecadienoic acid (13(S)-HODE), a primary oxidation product of linoleic acid, which plays a crucial role as a lipid mediator in cellular signaling. The "d4" in its name indicates that four hydrogen atoms have been replaced with deuterium, enhancing the molecule′s stability and making it particularly useful in analytical studies where precise tracking of its behavior and interactions is required. This modification allows for more accurate mass spectrometric analysis by reducing background noise and improving signal clarity. In research, 13(S)-HODE-d4 is employed to study lipid peroxidation processes and the role of fatty acid metabolites in cell signaling pathways. The molecule is particularly significant for its involvement in modulating inflammatory responses and regulating gene expression related to oxidative stress mechanisms. By using this deuterated compound, researchers can trace and quantify the metabolic pathways of 13(S)-HODE without altering its biological function, thereby providing insights into how lipid mediators influence cellular processes. This research is fundamental for understanding the complex interactions within lipid signaling networks and their impact on cellular homeostasis and response to environmental changes.