1-O-Methyl-2-deoxy-D-ribose (CAS 60134-26-1)
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1-O-Methyl-2-deoxy-D-ribose is a modified sugar molecule that is significant in the field of synthetic and bioorganic chemistry. Researchers study this compound for its role in the synthesis of nucleoside analogs, which are of interest for their potential to modulate biological processes involving DNA and RNA. Due to the absence of the 2′-hydroxyl group, this deoxy sugar is particularly relevant in the construction of DNA mimics that are resistant to enzymatic degradation. Studies involving 1-O-Methyl-2-deoxy-D-ribose also explore its incorporation into oligonucleotides to investigate the structural and functional implications of sugar modifications on nucleic acid stability and hybridization properties. Additionally, the methoxy group at the 1-position serves as a protective group that can be selectively removed to reveal reactive hydroxyl functionalities, making it useful in stepwise chemical synthesis. The compound is further used in the development of labeled probes for detecting specific nucleic acid sequences or for probing the activity of enzymes that interact with sugars and nucleosides.
1-O-Methyl-2-deoxy-D-ribose (CAS 60134-26-1) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-O-Methyl-2-deoxy-D-ribose, 1 g | sc-255854 | 1 g | $89.00 |