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1-hydroxycyclohexanecarboxylic acid (CAS 1123-28-0)

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Alternate Names:
1-hydroxycyclohexane-1-carboxylic acid
CAS Number:
1123-28-0
Purity:
≥95%
Molecular Weight:
144.17
Molecular Formula:
C7H12O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Hydroxycyclohexanecarboxylic acid (1-HCHC), also referred to as 1-hydroxycyclohexane carboxylic acid or 1-cyclohexylhydroxyacetic acid, emerges as a notable organic compound within the hydroxy acid family. Its physical manifestation takes the form of a white solid with a melting point of 155-156° C. In scientific research, 1-hydroxycyclohexanecarboxylic acid assumes a prominent role as a vital reagent for the synthesis of various compounds. Moreover, 1-hydroxycyclohexanecarboxylic acid finds utility as a substrate for enzymatic reactions aimed at synthesizing polyunsaturated fatty acids, such as arachidonic acid. Remarkably, 1-hydroxycyclohexanecarboxylic acid exhibits inhibitory properties toward the enzyme cyclooxygenase (COX). By impeding the activity of COX, 1-hydroxycyclohexanecarboxylic acid effectively reduces the production of prostaglandins.


1-hydroxycyclohexanecarboxylic acid (CAS 1123-28-0) References

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  6. An Unusual Domino Claisen− Conia Reaction Producing 3, 5‐Dispirodihydrofuran‐2, 4‐diones  |  Schobert, R., Siegfried, S., Gordon, G., Nieuwenhuyzen, M., & Allenmark, S. 2001. European Journal of Organic Chemistry. 2001(10): 1951-1958.
  7. 3‐Functionalized Tetronic Acids From Domino Rearrangement/Cyclization/Ring‐Opening Reactions of Allyl Tetronates  |  Schobert, R., Gordon, G. J., Bieser, A., & Milius, W. 2003. European Journal of Organic Chemistry. 2003(18): 3637-3647.
  8. Structural diversity-guided convenient construction of functionalized polysubstituted butenolides and lactam derivatives  |  Ke, S., Zhang, Y. N., Shu, W., Zhang, Z., Shi, L., Liang, Y.,.. & Yang, Z. 2011. Comptes Rendus Chimie. 14(12): 1071-1079.
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-hydroxycyclohexanecarboxylic acid, 250 mg

sc-273341
250 mg
$161.00