1-Ethynyl-4-phenoxybenzene (CAS 4200-06-0)
QUICK LINKS
1-Ethynyl-4-phenoxybenzene is a chemical compound utilized in organic chemistry research, particularly in the synthesis of complex organic molecules. It serves as a versatile building block in the construction of conjugated systems due to its phenyl and ethynyl groups, which are pivotal in cross-coupling reactions. Chemists study 1-Ethynyl-4-phenoxybenzene for its potential to form polymers with specific electronic properties, making it relevant for research in materials science, especially in the context of developing new semiconductors or conductive materials. In the realm of catalysis, it is used to understand the conditions under which carbon-carbon triple bonds participate in various catalytic transformations. Additionally, its phenoxy moiety is of interest for the introduction of ether functionalities into molecules, which can significantly alter the physical and chemical properties of the resultant compounds.
1-Ethynyl-4-phenoxybenzene (CAS 4200-06-0) References
- Isolable gold(I) complexes having one low-coordinating ligand as catalysts for the selective hydration of substituted alkynes at room temperature without acidic promoters. | Leyva, A. and Corma, A. 2009. J Org Chem. 74: 2067-74. PMID: 19170603
- Rational design of 5-phenyl-3-isoxazolecarboxylic acid ethyl esters as growth inhibitors of Mycobacterium tuberculosis. a potent and selective series for further drug development. | Lilienkampf, A., et al. 2010. J Med Chem. 53: 678-88. PMID: 20000577
- Synthesis and SAR of 1,3-thiazolyl thiophene and pyridine derivatives as potent, orally active and S1P₃-sparing S1P₁ agonists. | Asano, M., et al. 2012. Bioorg Med Chem Lett. 22: 3083-8. PMID: 22487179
- Tuning the preference of thiodigalactoside- and lactosamine-based ligands to galectin-3 over galectin-1. | van Hattum, H., et al. 2013. J Med Chem. 56: 1350-4. PMID: 23281927
- Investigation of fluorinated and bifunctionalized 3-phenylchroman-4-one (isoflavanone) aromatase inhibitors. | Amato, E., et al. 2014. Bioorg Med Chem. 22: 126-34. PMID: 24345481
- Synthetic glycoconjugates inhibitors of tumor-related galectin-3: an update. | Campo, VL., et al. 2016. Glycoconj J. 33: 853-876. PMID: 27526114
- Room Temperature Metal-Catalyzed Oxidative Acylation of Electron-Deficient Heteroarenes with Alkynes, Its Mechanism, and Application Studies. | Sharma, S., et al. 2018. J Org Chem. 83: 12420-12431. PMID: 30238752
- Novel Electrophilic Warhead Targeting a Triple-Negative Breast Cancer Driver in Live Cells Revealed by 'Inverse Drug Discovery'. | Fan, Y., et al. 2021. J Med Chem. 64: 15582-15592. PMID: 34623802
- Efficient one-pot synthesis of biologically interesting diverse furo [2, 3-b] pyran-6-ones by rhodium (II)-catalyzed cascade reactions of diazo compound with ethynyl compounds | Magar, K. B. S., Lee, Y. R., & Kim, S. H. 2013. Tetrahedron. 69(44): 9294-9302.
- Hydration of aromatic alkynes catalyzed by a self-assembled hexameric organic capsule | La Sorella, G., Sperni, L., Ballester, P., Strukul, G., & Scarso, A. 2016. Catalysis Science & Technology. 6(15): 6031-6036.
- Synthesis and characterization of luminescent 2,7-disubstituted silafluorenes | Hammerstroem, D. W., Braddock-Wilking, J., & Rath, N. P. 2016. Journal of Organometallic Chemistry. 813: 110-118.
- Luminescent 2,7-disubstituted germafluorenes | Hammerstroem, D. W., Braddock-Wilking, J., & Rath, N. P. 2017. Journal of Organometallic Chemistry. 830: 196-202.
- Nickel/Zinc Iodide Co‐catalytic Asymmetric [2+ 2] Cycloaddition Reactions of Azabenzonorbornadienes with Terminal Alkynes | Chen, J., Xu, X., He, Z., Qin, H., Sun, W., & Fan, B. 2018. Advanced Synthesis & Catalysis. 360(3): 427-431.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-Ethynyl-4-phenoxybenzene, 1 g | sc-253932 | 1 g | $126.00 |