Date published: 2026-3-19

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1-Cyclohexenyl trifluoromethanesulfonate (CAS 28075-50-5)

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CAS Number:
28075-50-5
Purity:
97%
Molecular Weight:
230.20
Molecular Formula:
C7H9F3O3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Cyclohexenyl trifluoromethanesulfonate (1-CHTMS) is a highly versatile reagent widely employed in synthetic organic chemistry, specifically for the synthesis of diverse compounds. Its significance lies in serving as a fundamental building block for complex molecule synthesis. The reactivity exhibited by 1-Cyclohexenyl trifluoromethanesulfonate renders it an invaluable tool for the synthesis of a wide array of compounds. Within material science, 1-Cyclohexenyl trifluoromethanesulfonate acts as a catalyst in the synthesis of polymers and copolymer systems. Furthermore, in the realm of biochemistry, it serves as a reagent in the synthesis of proteins and peptides. The high reactivity of 1-Cyclohexenyl trifluoromethanesulfonate arises from its ability to form covalent bonds with a diverse range of substrates. This occurs when the 1-Cyclohexenyl trifluoromethanesulfonate molecule donates an electron pair to the substrate, resulting in the formation of a new covalent bond. Subsequently, this covalent bond undergoes cleavage upon substrate oxidation, leading to the liberation of the 1-Cyclohexenyl trifluoromethanesulfonate molecule.


1-Cyclohexenyl trifluoromethanesulfonate (CAS 28075-50-5) References

  1. The palladium-catalyzed trifluoromethylation of vinyl sulfonates.  |  Cho, EJ. and Buchwald, SL. 2011. Org Lett. 13: 6552-5. PMID: 22111687
  2. Influence of catalyst structure and reaction conditions on anti- versus syn-aminopalladation pathways in Pd-catalyzed alkene carboamination reactions of N-allylsulfamides.  |  Fornwald, RM., et al. 2014. Chemistry. 20: 8782-90. PMID: 24938206
  3. Enantioselective Hydroalkenylation of Olefins with Enol Sulfonates Enabled by Dual Copper Hydride and Palladium Catalysis.  |  Schuppe, AW., et al. 2021. J Am Chem Soc. 143: 5330-5335. PMID: 33784090
  4. A Dual CuH- and Pd-Catalyzed Stereoselective Synthesis of Highly Substituted 1,3-Dienes.  |  Hou, CJ., et al. 2021. Org Lett. 23: 8816-8821. PMID: 34726414

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Cyclohexenyl trifluoromethanesulfonate, 5 g

sc-224633
5 g
$148.00