1,2-Dichloro-4-nitrobenzene (CAS 99-54-7)
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1,2-Dichloro-4-nitrobenzene is a chemical compound that functions as an intermediate in the synthesis of various organic compounds. Its mechanism of action involves participating in nucleophilic aromatic substitution reactions, where it undergoes substitution reactions with other organic compounds to form new chemical products. 1,2-Dichloro-4-Nitrobenzene is known to react with a variety of nucleophiles, such as amines and thiols, to form substituted products with different functional groups. 1,2-Dichloro-4-nitrobenzene is utilized as a building block for the synthesis of agrochemicals, and other fine chemicals. Its ability to undergo substitution reactions may be versatile for the creation of complex organic molecules with specific functional groups. 1,2-Dichloro-4-Nitrobenzene′s role in the laboratory setting involves its reactivity and ability to facilitate the synthesis of diverse chemical compounds for various experimental purposes.
1,2-Dichloro-4-nitrobenzene (CAS 99-54-7) References
- Structural determinants in domain II of human glutathione transferase M2-2 govern the characteristic activities with aminochrome, 2-cyano-1,3-dimethyl-1-nitrosoguanidine, and 1,2-dichloro-4-nitrobenzene. | Hansson, LO., et al. 1999. Protein Sci. 8: 2742-50. PMID: 10631991
- Characterization of phenotypes in Gstm1-null mice by cytosolic and in vivo metabolic studies using 1,2-dichloro-4-nitrobenzene. | Fujimoto, K., et al. 2006. Drug Metab Dispos. 34: 1495-501. PMID: 16760226
- Methemoglobinemia induced by 1,2-dichloro-4-nitrobenzene in mice with a disrupted glutathione S-transferase Mu 1 gene. | Arakawa, S., et al. 2010. Drug Metab Dispos. 38: 1545-52. PMID: 20562208
- Vibrational spectroscopic, first-order hyperpolarizability and HOMO, LUMO studies of 1,2-dichloro-4-nitrobenzene based on Hartree-Fock and DFT calculations. | Arivazhagan, M. and Jeyavijayan, S. 2011. Spectrochim Acta A Mol Biomol Spectrosc. 79: 376-83. PMID: 21466973
- Molecular structure, vibrational spectra, HOMO, LUMO and NMR studies of 1,2-dichloro-4-nitrobenzene and 2,3,5,6-tetrachloro-1-nitrobenzene based on density functional calculations. | Krishnakumar, V., et al. 2012. Spectrochim Acta A Mol Biomol Spectrosc. 86: 196-204. PMID: 22104327
- Target-Site Mutations and Glutathione S-Transferases Are Associated with Acequinocyl and Pyridaben Resistance in the Two-Spotted Spider Mite Tetranychus urticae (Acari: Tetranychidae). | Choi, J., et al. 2020. Insects. 11: PMID: 32784738
- Characterization of the Glutathione S-Transferases Involved in Styrene Degradation in Gordonia rubripertincta CWB2. | Lienkamp, AC., et al. 2021. Microbiol Spectr. 9: e0047421. PMID: 34319142
- Biochemical characterization and peptide mass fingerprinting of two glutathione transferases from Biomphalaria alexandrina snails (Gastropoda: Planorbidae). | Abdalla, AM. and Abdel Karim, GSA. 2022. J Genet Eng Biotechnol. 20: 99. PMID: 35792934
- Analysis of Essential Isoprene Metabolic Pathway Proteins in Variovorax sp. Strain WS11. | Rix, GD., et al. 2023. Appl Environ Microbiol. 89: e0212222. PMID: 36840579
- Ameliorative effects of glycine on cobalt chloride-induced hepato-renal toxicity in rats. | Iji, OT., et al. 2023. Animal Model Exp Med. 6: 168-177. PMID: 37141004
- Potent GST Ketosteroid Isomerase Activity Relevant to Ecdysteroidogenesis in the Malaria Vector Anopheles gambiae. | Musdal, Y., et al. 2023. Biomolecules. 13: PMID: 37371556
- Ursodeoxycholic acid reduces the systemic toxicity of 1,2-dichloro,4-nitrobenzene by stimulating hepatic glutathione S-transferase in mice. | Kitani, K., et al. 1994. Life Sci. 54: 983-9. PMID: 8139388
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1,2-Dichloro-4-nitrobenzene, 100 g | sc-237676 | 100 g | $36.00 |