1-(1-Naphthyl)piperazine·HCl (CAS 57536-86-4)
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1-(1-Naphthyl)piperazine·HCl is the hydrochloride salt preparation of 1-(1-Naphthyl)piperazine, a small molecule modulator of the 5-HT (serotonin) receptors with mixed activity. 1-(1-Naphthyl)piperazine demonstrates agonist activity at the 5-HT1A receptor and antagonist activity at the 5-HT2A/2C receptor. Blockade of the peripheral vascular pressor response to 5-HT and attenuation of the stimulus properties of 2,5-dimethoxy-4-methyl-amphetamine, both associated with the 5-HT2 receptor, are correlated to the 5-HT2 antagonism produced by 1-(1-Naphthyl)piperazine. The agonism of 5-HT1A produced by 1-(1-Naphthyl)piperazine is correlated to a reduction in 5-HT turnover and an increase in serum corticosterone. 1-(1-Naphthyl)piperazine·HCl is an inhibitor of SR-2A and an activator of SR-1A.
1-(1-Naphthyl)piperazine·HCl (CAS 57536-86-4) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-(1-Naphthyl)piperazine·HCl, 20 mg | sc-201139 | 20 mg | $53.00 | |||
1-(1-Naphthyl)piperazine·HCl, 100 mg | sc-201139A | 100 mg | $214.00 |