VEZF1 Antibody (ZNF5J141): sc-81134
- VEZF1 Antibody (ZNF5J141) is a mouse monoclonal IgG1, cited in 1 publications, provided at 100 µg/ml
- raised against a recombinant protein corresponding to an internal region of VEZF1 of human origin
- recommended for detection of VEZF1 of mouse, rat and human origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for VEZF1 Antibody (ZNF5J141). This work is in progress.
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VEZF1 Antibody (ZNF5J141) is a mouse monoclonal IgG1 antibody that detects VEZF1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). VEZF1, also known as vascular endothelial zinc finger 1 or ZNF161, is a crucial nuclear-localizing zinc-finger protein that plays a significant role in the regulation of endothelial gene expression, particularly in cardiovascular development. VEZF1 is predominantly expressed in the kidneys and skeletal muscle, where VEZF1 functions as a transcription factor that modulates the expression of endothelin-1 (ET-1) by binding to the CT/GC-rich region of the ET-1 promoter. VEZF1′s ability to activate ET-1 expression is vital for proper assembly of the cardiovascular system during early embryonic development, as VEZF1 influences the formation and maintenance of vascular structures. Additionally, VEZF1′s interaction with histone modifying proteins through its Krüppel-type DNA binding domain and KRAB domain underscores VEZF1′s importance in transcriptional regulation and chromatin remodeling, making anti-VEZF1 antibody (ZNF5J141) an essential tool for researchers studying vascular biology and related fields.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
VEZF1 Antibody (ZNF5J141) | sc-81134 | 100 µg/ml | $339.00 |