

TIP60 Antibody (T4D2) is a mouse monoclonal IgG2b antibody that detects TIP60 in human samples through applications such as western blotting (WB), immunofluorescence (IF), and immunohistochemistry. TIP60, also known as TAT-interacting protein 60, is a crucial chromatin-associated protein that functions as a histone acetyltransferase (HAT), playing a significant role in the regulation of gene expression and chromatin remodeling. anti-TIP60 antibody (T4D2) recognizes a protein that modifies histones through acetylation, which alters chromatin structure and accessibility, thereby influencing transcriptional activation. TIP60 is particularly notable for its interactions with various transcriptional coactivators and nuclear hormone receptors, enhancing the transcriptional response to steroid hormones such as androgens, estrogens, and progestins. Additionally, TIP60 has been implicated in DNA damage response pathways, where TIP60 acts as a coactivator for the HIV TAT protein and is involved in the recruitment of repair factors to sites of DNA damage. TIP60 (T4D2) antibody is an essential tool for researchers studying the intricate mechanisms of gene regulation and the role of histone modifications in cellular processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TIP60 Antibody (T4D2) | sc-81757 | 200 µg/ml | $322.00 | |||
TIP60 Antibody (T4D2): m-IgGκ BP-HRP Bundle | sc-534487 | 200 µg Ab; 40 µg BP | $361.00 | |||
TIP60 Antibody (T4D2): m-IgG2b BP-HRP Bundle | sc-549261 | 200 µg Ab; 10 µg BP | $361.00 |