Syntaxin 7 Antibody (G-7): sc-514157

Syntaxin 7 Antibody (G-7) is a mouse monoclonal IgG1 antibody that detects Syntaxin 7 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Syntaxin 7 plays a crucial role in the vesicular transport system, particularly in the fusion of late endosomes, which is vital for maintaining cellular homeostasis and facilitating intracellular communication. Syntaxin 7 is predominantly located in the endosomal compartments of cells, where Syntaxin 7 interacts with other SNARE proteins, such as Syntaxin 8, vti1b, and VAMP-8, to form a functional SNARE complex. The proper functioning of this complex is essential for the fusion of vesicles with target membranes, a process that is critical for the delivery of proteins and lipids to their appropriate destinations within the cell. Notably, Syntaxin 7′s expression increases in B16 melanoma cells during melanogenesis, indicating Syntaxin 7′s involvement in this specific cellular process. Syntaxin 7′s ability to bind α-SNAP and participate in the formation of stable SNARE complexes underscores Syntaxin 7′s importance in regulating membrane fusion events, which are fundamental to various cellular functions, including secretion, nutrient uptake, and signal transduction.

The preferred Syntaxin 7 antibody is Syntaxin 7 Antibody (A-1): sc-514017.