Synaptogyrin-1 Antibody (A-6): sc-393456
- Synaptogyrin-1 Antibody (A-6) is a mouse monoclonal IgG2a κ Synaptogyrin-1 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 208-231 at the C-terminus of Synaptogyrin-1 of human origin
- Synaptogyrin-1 Antibody (A-6) is recommended for detection of Synaptogyrin-1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-Synaptogyrin-1 Antibody (A-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Synaptogyrin-1 Antibody (A-6) for WB and IHC(P) applications. This reagent is now offered in a bundle with Synaptogyrin-1 Antibody (A-6) (see ordering information below).
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Synaptogyrin-1 Antibody (A-6) is a mouse monoclonal IgG2a kappa light chain antibody that detects Synaptogyrin-1 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-Synaptogyrin-1 antibody (A-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Synaptogyrin-1 plays a crucial role in synaptic transmission through localization to presynaptic vesicles in neuronal cells, where Synaptogyrin-1 regulates neurotransmitter release. This localization ensures efficient packaging and release of neurotransmitters in response to neuronal activity, facilitating communication between neurons. Synaptogyrin-1 belongs to a family of proteins including Synaptogyrin-2 and Synaptogyrin-3, which exhibit distinct expression patterns and functions, highlighting the importance of synaptogyrins in both neuronal and non-neuronal cells. Tyrosine phosphorylation in synaptogyrins suggests a regulatory mechanism influencing protein interactions and synaptic vesicle dynamics.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Synaptogyrin-1 Antibody (A-6) References:
- Cellugyrin and synaptogyrin facilitate targeting of synaptophysin to a ubiquitous synaptic vesicle-sized compartment in PC12 cells. | Belfort, GM. and Kandror, KV. 2003. J Biol Chem. 278: 47971-8. PMID: 12928441
- Characterization of synaptogyrin 3 as a new synaptic vesicle protein. | Belizaire, R., et al. 2004. J Comp Neurol. 470: 266-81. PMID: 14755516
- Essential components for a glutamatergic synapse between Merkel cell and nerve terminal in rats. | Hitchcock, IS., et al. 2004. Neurosci Lett. 362: 196-9. PMID: 15158013
- Patterns of gene dysregulation in the frontal cortex of patients with HIV encephalitis. | Masliah, E., et al. 2004. J Neuroimmunol. 157: 163-75. PMID: 15579294
- Cellugyrin induces biogenesis of synaptic-like microvesicles in PC12 cells. | Belfort, GM., et al. 2005. J Biol Chem. 280: 7262-72. PMID: 15590695
- Rat retinal dopaminergic neurons: differential maturation of somatodendritic and axonal compartments. | Witkovsky, P., et al. 2005. J Comp Neurol. 481: 352-62. PMID: 15593337
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Synaptogyrin-1 Antibody (A-6) | sc-393456 | 200 µg/ml | $322.00 | |||
Synaptogyrin-1 Antibody (A-6): m-IgG Fc BP-HRP Bundle | sc-526254 | 200 µg Ab; 10 µg BP | $361.00 | |||
Synaptogyrin-1 Antibody (A-6) AC | sc-393456 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Synaptogyrin-1 Antibody (A-6) HRP | sc-393456 HRP | 200 µg/ml | $322.00 | |||
Synaptogyrin-1 Antibody (A-6) FITC | sc-393456 FITC | 200 µg/ml | $336.00 | |||
Synaptogyrin-1 Antibody (A-6) PE | sc-393456 PE | 200 µg/ml | $349.00 | |||
Synaptogyrin-1 Antibody (A-6) Alexa Fluor® 488 | sc-393456 AF488 | 200 µg/ml | $364.00 | |||
Synaptogyrin-1 Antibody (A-6) Alexa Fluor® 546 | sc-393456 AF546 | 200 µg/ml | $364.00 | |||
Synaptogyrin-1 Antibody (A-6) Alexa Fluor® 594 | sc-393456 AF594 | 200 µg/ml | $364.00 | |||
Synaptogyrin-1 Antibody (A-6) Alexa Fluor® 647 | sc-393456 AF647 | 200 µg/ml | $364.00 | |||
Synaptogyrin-1 Antibody (A-6) Alexa Fluor® 680 | sc-393456 AF680 | 200 µg/ml | $364.00 | |||
Synaptogyrin-1 Antibody (A-6) Alexa Fluor® 790 | sc-393456 AF790 | 200 µg/ml | $364.00 | |||
Synaptogyrin-1 (A-6) Neutralizing Peptide | sc-393456 P | 100 µg/0.5 ml | $69.00 |