Sodium dodecyl sulfate CAS: 151-21-3
Sodium dodecyl sulfate is an anionic detergent and protein denaturant.

Sodium dodecyl sulfate (CAS 151-21-3)

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Alternate Names: Sodium dodecyl sulfate is also known as SDS.
Application Sodium dodecyl sulfate is an anionic detergent and protein denaturant
CAS 등록번호: 151-21-3
순도: ≥96%
분자량: 288.38
분자식: C12H25O4S•Na
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
* 참조분석증명서대량의 측정 데이터(함수량포함).

Sodium dodecyl sulfate (SDS) is an anionic detergent used to solubilize and denature proteins in protein extraction and SDS-PAGE. Sodium dodecyl sulfate is useful in electrophoretic separation of proteins and lipids. Sodium dodecyl sulfate is also used in a variety of hybridization and molecular biology techniques. Sodium dodecyl sulfate is effective in both ionic and anionic conditions. Sodium dodecyl sulfate unravels proteins by binding to peptide chains and imparting a negative charge on the protein; this causes the protein to unfold eliminating shape as a factor for gel separation.

Also available in solution form: SDS (20% Solution) (sc-24950).


References

1. Laemmli, U.K. 1970. Nature. 227(5259): 680-685. PMID: 5432063

2. Weber, K. and Kuter, D.J. 1971. J. Biol. Chem. 246(14): 4504-4509. PMID: 5106387

3. Harewood, K. and Wolff, J.S. 1973. Anal. Biochem. 55(2): 573-581. PMID: 4201521

4. Hayashi, K. 1975. Anal. Biochem. 67(2): 503-506. PMID: 1163770

5. Kapp, O.H. and Vinogradov, S.N. 1978. Anal. Biochem. 91(1): 230-235. PMID: 9762103

6. Womack, M.D. et al. 1983. Biochim. Biophys. Acta. 733(2): 210-215. PMID: 6882760

7. Grohs, R.A. et al. 1991. Anal. Chem. 63(4): 384-390. PMID: 1823727

8. Gallagher, S.R. 2007. Curr Protoc Cell Biol. Chapter6 : Unit 6.1. PMID: 18228518

Appearance :
Crystalline
Physical State :
Solid
용해도 :
Soluble in water (150 g/L at 20° C), and ethanol (partly soluble).
저장 :
Store at room temperature
녹는점 :
204-207° C (lit.)
IC50 :
Human HepG2/C3A cells: IC50 = 0.22 nM
Ki 데이타 :
Displacement of C18-Aib-lucifer yellow from HIV1 envelope glycoprotein gp41 Fe(env2.0)3 receptor: Ki= 2000 nM
pK Values :
pKa: -3.29 (Predicted)
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
WGK Germany :
2
RTECS :
WT1050000
PubChem CID :
3423265
Merck Index :
14: 8636
MDL Number :
MFCD00036175
EC Number :
205-788-1
Beilstein Registry :
3599286
SMILES :
CCCCCCCCCCCCOS(=O)(=O)[O-].[Na+]

SDS(MSDS)다운로드

분석증명서

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Sodium dodecyl sulfate (CAS 151-21-3)  논문정보

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Citations 1 to 8 of {3} total

PMID: # 26780454  Karimzadeh, F. et al. 2016. Mol. Neurobiol.

PMID: # 27038753  Aligholi, H. et al. 2016. Brain research. 1642: 197-208.

PMID: # 26141394  Wan, D. et al. 2015. Toxicol. Sci. 147: 326-38.

PMID: # 24962405  Ahn, JH. et al. 2014. J. Vet. Sci. 15: 335-42.

PMID: # 22393286  Akhtar, MJ. et al. 2012. Int J Nanomedicine. 7: 845-57.

PMID: # 22245848  Ahmad, J. et al. 2012. Toxicol. Appl. Pharmacol. 259: 160-8.

PMID: # 21606120  2011. Mol. Hum. Reprod. 17: 693-701.

PMID: # 28285257  Colloids Surf B Biointerfaces. 320-326.

Citations 1 to 8 of {3} total
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