SCYL3 Antibody (G-8) is a high quality monoclonal SCYL3 antibody (also designated SCYL3 antibody) suitable for the detection of the SCYL3 protein of mouse, rat and human origin. SCYL3 Antibody (G-8) is available as both the non-conjugated anti-SCYL3 antibody form, as well as multiple conjugated forms of anti-SCYL3 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. SCYL3 (SCY1-like 3), also known as Protein-associating with the carboxyl-terminal domain of ezrin, is a 742 amino acid protein that belongs to the protein kinase superfamily. The SCYL3 protein contains an N-terminal myristoylation consensus sequence, followed by a protein kinase domain, 2 tandemly arrayed HEAT motifs composed of pairs of antiparallel alpha helices, and a C-terminal ezrin-binding domain. The SCYL3 protein may be phosphorylated. Ubiquitously expressed, the SCYL3 protein colocalizes with Ezrin, actin and HCAM in lamellipodia. The SCYL3 protein may be myristoylated, which may target SCYL3 to Golgi compartment. Existing as two alternatively spliced isoforms, the SCYL3 gene contains 14 exons, is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly and mosquito, and maps to human chromosome 1q24.2.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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