안티-SAP 62 항체 A-3 는 마우스 monoclonal IgG1 κ SAP 62 항체, 2간행물에 인용, 이며 200 µg/ml으로 제공합니다.
human origin의 SAP 62에서 C-terminus에 위치한 293-429 아미노산을 항원으로 사용하였습니다.
안티-SAP 62 항체 (A-3)는 WB, IP, IF, IHC(P) and ELISA으로 mouse, rat and human유래의 SAP 62 를 감지하는 데에 추천한다.
IP를 위해 agarose ;WB, IHC(P) and ELISA를 위해 HRP ;또는 IF, IHC(P) and FCM를 위해 phycoerythrin or FITC 에 결합된 Anti-SAP 62 항체 (A-3)를 제공한다.
WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for SAP 62 Antibody (A-3) for WB and IHC(P) applications. These reagents are now offered in bundles with SAP 62 Antibody (A-3) (see ordering information below).
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SAP 62 Antibody (A-3) is a high quality monoclonal SAP 62 antibody (also designated SAP 62 antibody) suitable for the detection of the SAP 62 protein of mouse, rat and human origin. SAP 62 Antibody (A-3) is available as both the non-conjugated anti-SAP 62 antibody form, as well as multiple conjugated forms of anti-SAP 62 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. SAP 62, also known as SF3A2 (Splicing factor 3A subunit 2), PRP11, PRPF11 or SF3a66, is a 464 amino acid protein that contains one matrin-type zinc finger and belongs to the SF3A2 family. Localized to the nucleus, SAP 62 is a subunit of the SF3A splicing factor, a heterotrimeric complex comprised of three subunits that act in tandem to mediate the binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. The SF3A complex is necessary for the conversion of 15S U2 snRNP into the active 17S protein that performs directly in pre-mRNA splicing events. Functioning as the second subunit of the complex, SAP 62 interacts with subunit 1 (SAP 114) via its N-terminus while simultaneously binding to 15S U2 snRNP via its zinc finger domain. In addition to its role in RNA splicing, SAP 62 is thought to act independently as a microtubule-binding protein.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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