


RD3 Antibody (D-11) is a mouse monoclonal IgG1 antibody that detects RD3 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RD3, also known as retinal degeneration 3 or LCA12, is a crucial 195 amino acid protein predominantly expressed in the retina, where RD3 plays a significant role in forming subnuclear protein complexes essential for various cellular processes, including transcription and splicing. Proper functioning of RD3 is vital for maintaining photoreceptor health and function; defects in RD3 lead to Leber congenital amaurosis type 12, a severe condition characterized by minimal or absent retinal photoreceptor activity in affected infants. This impairment underscores RD3′s importance in visual development and highlights anti-RD3 antibody (D-11) as a valuable tool for studying molecular mechanisms underlying retinal diseases and advancing research in gene therapy and other therapeutic strategies aimed at restoring vision.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RD3 Antibody (D-11) | sc-514692 | 200 µg/ml | $322.00 | |||
RD3 Antibody (D-11): m-IgG Fc BP-HRP Bundle | sc-538684 | 200 µg Ab; 10 µg BP | $361.00 | |||
RD3 Antibody (D-11): m-IgGκ BP-HRP Bundle | sc-536344 | 200 µg Ab; 40 µg BP | $361.00 | |||
RD3 Antibody (D-11): m-IgG1 BP-HRP Bundle | sc-545829 | 200 µg Ab; 20 µg BP | $361.00 |