PTP CD45 Inhibitor 억제제 (CAS 345630-40-2)
5
4
3
2
1
Alternate Names:
Protein Tyrosine Phosphatase CD45 Inhibitor; N-(9,10-dihydro-9,10-dioxo-2-phenanthrenyl)-2,2-dimethyl-propanamide
Application
PTP CD45 Inhibitor is a cell permeable potent reversible inhibitor of CD45
CAS 등록번호:
345630-40-2
순도:
≥97%
분자량:
307.34
분자식:
C19H17NO3
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
PTP CD45 Inhibitor is a cell-permeable, potent, selective, competitive, and reversible inhibitor of CD45 (IC50 = 200 nM or 3.8 μM using pNPP or phosphorylated Ick505 peptide as a substrate, respectively). PTP CD45 Inhibitor is not able to effectively inhibit PTPIB (IC50 <30 μM using phosphorylated Ick505 peptide as a substrate). The phenanthrenedione group does not function as a thiol oxidizing agent.
References
1. Urbanek, R.A., et al. 2001. J. Med. Chem. 44: 1777-1793. PMID: 11356112
Physical State
:
Solid
용해도
:
Soluble in DMF (10 mg/ml), and DMSO (10 mg/ml).
저장
:
Store at 4° C
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
PubChem CID
:
SMILES
:
CC(C)(C)C(=O)NC1=CC2=C(C=C1)C3=CC=CC=C3C(=O)C2=O
SDS(MSDS)다운로드
분석증명서
PDF문서를 열람,
프린트와 코멘트를 작성하려면 Adobe Acrobat Reader가 필요합니다.