Protein Synthesis Initiation Inhibitor, NSC 119889 MF: C20H8Br4O5
MW: 647.9
A cell-permeable, xanthenyl compound that prevents protein synthesis.

Protein Synthesis Initiation Inhibitor, NSC 119889

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Alternate Names: 3,4,5,6-tetrabromofluorescein
Application Protein Synthesis Initiation Inhibitor, NSC 119889 is a cell-permeable, xanthenyl compound that prevents protein synthesis
순도: ≥95%
분자량: 647.9
분자식: C20H8Br4O5
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
* Refer to Certificate of Analysis for lot specific data (including water content).

A cell-permeable, xanthenyl compound that prevents mRNA-ribosome interaction and inhibits 5'-mediated/cap-dependent initiation of protein synthesis.


References

Novac, O., et al. 2004. Nucleic Acids Res. 32, 902. Tan, Y.J., et al. 2003. J. Cancer Res. Clin. Oncol. 129, 437.

Physical State :
Solid
용해도 :
Soluble in DMSO (200 mg/ml), and methanol.
저장 :
Store at 4° C
비등점 :
762.93° C at 760 mmHg (Predicted)
밀도 :
2.42 g/cm3 (Predicted)
굴절률 :
n20D 1.85 (Predicted)
IC50 :
arginine methyl transferase: IC50 = 1.41 µM (human); arginine methyl transferase: IC50 = 0.78 µM (yeast)
Ki 데이타 :
NCp7: Ki> 10 µM
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
PubChem CID :
SMILES :
C1=CC2=C(C=C1O)OC3=CC(=O)C=CC3=C2C4=C(C(=C(C(=C4Br)Br)Br)Br)C(=O)O

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Protein Synthesis Initiation Inhibitor, NSC 119889  논문정보

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인용 1 to 1 of 1 합계

PMID: # 27892500  Sci Rep. 37905.

인용 1 to 1 of 1 합계
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