Propofol β-D-glucuronide CAS: 114991-26-3
MF: C18H26O7
MW: 354.39
A Propofol metabolite.

Propofol β-D-glucuronide (CAS 114991-26-3)

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Alternate Names: 2,6-Bis(1-methylethyl)phenyll β-D-glucopyranosiduronic acid; Propofol Glucuronide
Application Propofol β-D-glucuronide is a Propofol metabolite
CAS 등록번호: 114991-26-3
순도: ≥98%
분자량: 354.39
분자식: C18H26O7
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
* Refer to Certificate of Analysis for lot specific data (including water content).

Propofol Glucuronide is a metabolite following rapid clearance of Propofol linked with glucuronidation by the uridine diphosphate glucuronosyltransferases. The compound has been used as a standard to develop a liquid chromatography and mass spectroscopy bioanalytical assay for in vitro enzyme kinetics and in vivo pharmacokinetics of of glucuronides.


References

1. Favetta, P., et al. 2002. Br J Anaesth. 88: 653-658. PMID: 12067002
2. Soars, M.G., et al. 2002. J Pharmacol Toxicol Methods. 47: 161-168. PMID: 12628307
3. Fujiwara, R., et al. 2007. Drug Metab. Dispos. 35: 747-757. PMID: 17293379

Physical State :
Solid
용해도 :
Soluble in DMSO, Ethanol and Methanol
저장 :
Store at -20° C
녹는점 :
142-143° C
비등점 :
~562.4° C at 760 mmHg (Predicted)
밀도 :
~1.3 g/cm3 (Predicted)
굴절률 :
n20D 1.58 (Predicted)
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
PubChem CID :
SMILES :
CC(C)C1=C(C(=CC=C1)C(C)C)O[[email protected]]2[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]](O2)C(=O)O)O)O)O

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Propofol β-D-glucuronide (CAS 114991-26-3)  논문정보

다른 사용자의 Propofol β-D-glucuronide (CAS 114991-26-3)사용법보기. 클릭하여 PubMed entry보기 .

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PMID: # 24470170  Yamamoto, K. et al. 2014. European journal of drug metabolism and pharmacokinetics. 39: 195-202.

PMID: # 25985579  Mukai, M. et al. 2014. Die Pharmazie. 69: 829-32.

PMID: # 23562620  Arch Biochem Biophys. 143-9.

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