PLAP CAS: 137314-60-4
MF: C106H184N28O30
MW: 2330.8
A phospholipase A2 activating peptide fragment consisting of 21 residues.

PLAP (CAS 137314-60-4)

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Synonym: Phospholipase A2 activating peptide
Application A phospholipase A2 activating peptide fragment consisting of 21 residues
CAS 등록번호: 137314-60-4
순도: ≥97%
분자량: 2330.8
분자식: C106H184N28O30
* 참조분석증명서대량의 측정 데이터(함수량포함).
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The phospholipase A2 activating protein (PLAP) is a 21-residue fragment that spans the PLAP-melittin homology sequence and is a member of the β-transducin (Gβ) superfamily. The peptide activates phospholipase A2 (10-fold at 1 μg/ml) in BC3H1 cell sonicates, as well as stimulates Golgi membrane tubulation and retrograde trafficking to the ER. Research indicates that PLAP peptide activates Ca(2+)-dependent phospholipase A(2) cPLA(2) in vascular smooth muscle cells, leading to arachidonic acid release and apoptosis.


References

1. Peitsch, M.C., 1993. Trends Biochem. Sci. 18: 292-293. PMID: 8236442
2. Wang, H., et al. 1995. Gene. 161: 237-241. PMID: 7665086
3. Polizotto, R.S., et al. 1999. J. Cell. Biochem. 74: 670-683. PMID: 10440936
4. Pilane, C.M., et al. 2004. J. Cell. Physiol. 198: 48-52. PMID: 14584043

Physical State :
Solid
시퀀스 :
H-Glu-Ser-Pro-Leu-Ile-Ala-Lys-Val-Leu-Thr-Thr-Glu-Pro-Pro-Ile- Ile-Thr-Pro-Val-Arg-Arg-OH
용해도 :
Soluble in water.
저장 :
Store at -20° C
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
WGK Germany :
3

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