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Palmitoyl coenzyme A lithium salt (CAS 188174-64-3)

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Alternate Names:
Palmitoyl coenzyme A lithium salt is also known as n-Hexadecanoyl Coenzyme A.
Application:
Palmitoyl coenzyme A lithium salt is a long chain fatty acid (C16) that is covalently linked to Coenzyme A.
CAS Number:
188174-64-3
Purity:
≥90%
Molecular Weight:
1004.94 (free acid basis)
Molecular Formula:
C37H65N7O17P3S•xLi
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Palmitoyl coenzyme A lithium salt, a long-chain fatty acid derivative intricately linked to Coenzyme A, plays a pivotal role in the dynamic realm of cellular biochemistry, particularly in the process of palmitoylation. This biochemical modification, where a palmitate molecule is covalently attached to proteins, is for a myriad of cellular functions, notably in facilitating the binding of proteins to cell membranes. Such a mechanism is not only fundamental in the context of cellular signaling pathways but also in the modulation and extension of G-protein mediated signals, thereby influencing a broad spectrum of cellular processes. Furthermore, the utility of Palmitoyl coenzyme A lithium salt extends into the domain of developmental biology research, where it has been employed in experimental setups such as the microinjection into amphibian oocytes. This specific application aims to elucidate mechanisms underlying cellular activation, including the investigation of how the inhibition of key metabolic enzymes like citrate synthase can affect the activation process of eggs. Through these diverse roles, Palmitoyl coenzyme A lithium salt emerges as a versatile tool in the exploration of cellular signaling, protein modification, and the intricate dance of metabolic and signaling pathways that govern cellular and developmental biology.


Palmitoyl coenzyme A lithium salt (CAS 188174-64-3) References

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  2. Preferential hydrolysis of aberrant intermediates by the type II thioesterase in Escherichia coli nonribosomal enterobactin synthesis: substrate specificities and mutagenic studies on the active-site residues.  |  Guo, ZF., et al. 2009. Biochemistry. 48: 1712-22. PMID: 19193103
  3. n-3 PUFA as regulators of cardiac gene transcription: a new link between PPAR activation and fatty acid composition.  |  Di Nunzio, M., et al. 2009. Lipids. 44: 1073-9. PMID: 19859757
  4. Identification of DES1 as a vitamin A isomerase in Müller glial cells of the retina.  |  Kaylor, JJ., et al. 2013. Nat Chem Biol. 9: 30-6. PMID: 23143414
  5. Strategies for correcting very long chain acyl-CoA dehydrogenase deficiency.  |  Tenopoulou, M., et al. 2015. J Biol Chem. 290: 10486-94. PMID: 25737446
  6. Intrinsic Size Parameters for Palmitoylated and Carboxyamidomethylated Peptides.  |  Li, Z., et al. 2014. Int J Mass Spectrom. 368: 6-14. PMID: 26023288
  7. Application of An Improved HPLC-FL Method to Screen Serine Palmitoyl Transferase Inhibitors.  |  Bertini, S., et al. 2017. Molecules. 22: PMID: 28714922
  8. A microglial cell model for acyl-CoA oxidase 1 deficiency.  |  Raas, Q., et al. 2019. Biochim Biophys Acta Mol Cell Biol Lipids. 1864: 567-576. PMID: 30312667
  9. Biomarker responses and biotransformation capacity in Arctic and temperate benthic species exposed to polycyclic aromatic hydrocarbons.  |  Szczybelski, AS., et al. 2019. Sci Total Environ. 662: 631-638. PMID: 30703720
  10. The long-chain monounsaturated cetoleic acid improves the efficiency of the n-3 fatty acid metabolic pathway in Atlantic salmon and human HepG2 cells.  |  Østbye, TK., et al. 2019. Br J Nutr. 122: 755-768. PMID: 31288871
  11. Evaluating Hedgehog Acyltransferase Activity and Inhibition Using the Acylation-coupled Lipophilic Induction of Polarization (Acyl-cLIP) Assay.  |  Andrei, SA., et al. 2022. Methods Mol Biol. 2374: 13-26. PMID: 34562239
  12. De novo labeling and trafficking of individual lipid species in live cells.  |  Zhang, J., et al. 2022. Mol Metab. 61: 101511. PMID: 35504533
  13. Human Umbilical Vein Endothelial Cells Survive on the Ischemic TCA Cycle under Lethal Ischemic Conditions.  |  Mao, L., et al. 2022. J Proteome Res. 21: 2385-2396. PMID: 36074008
  14. Inhibition of brain Gz GAP and other RGS proteins by palmitoylation of G protein alpha subunits.  |  Tu, Y., et al. 1997. Science. 278: 1132-5. PMID: 9353196

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Palmitoyl coenzyme A lithium salt, 5 mg

sc-215668
5 mg
$231.00

Palmitoyl coenzyme A lithium salt, 10 mg

sc-215668A
10 mg
$392.00

Palmitoyl coenzyme A lithium salt, 25 mg

sc-215668B
25 mg
$820.00

Palmitoyl coenzyme A lithium salt, 100 mg

sc-215668C
100 mg
$2760.00

what is the stability of this product in water. At -20 or -80?

Asked by: JPV1
Thank you for contacting Santa Cruz Biotechnology. We are unable to provide this information.
Answered by: BlakeJ
Date published: 2024-03-14

Hello, I wonder solubility of Palmitoyl-CoA, What mg/ml? Is it soluble in water? Which means that I don't need to use DMSO?

Asked by: Lee Eun Young
This should be soluble at 50mg/ml in water.
Answered by: Technical Support
Date published: 2019-09-11
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Rated 5 out of 5 by from super fonctionnelJ'ai acheté le produit le mois passé et j'en suis très content.
Date published: 2020-02-12
Rated 5 out of 5 by from WangWang, W. et al. (PubMed 26029828) reported that elevated levels of Palmitoyl coenzyme A are required for required for Wnt ligand lipid modification and secretion. -SCBT Publication Review
Date published: 2015-04-08
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Palmitoyl coenzyme A lithium salt is rated 5.0 out of 5 by 2.
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