Date published: 2025-9-9

001 800-1338-3838

SCBT Portrait Logo
Seach Input

Nrf2 항체 (437C2a): sc-81342

4.0(8)
리뷰 쓰기질문하기

데이터 시트
  • Nrf2 항체(437C2a) 는 마우스 monoclonal IgG1κ, 29간행물에 인용, 이며 100 µg/ml으로 제공합니다.
  • human 기원의 Nrf2의 45 아미노산에 해당하는 재조합 단백질에 대해 제기됨
  • WB 와IP으로 human origin의 Nrf2을 검출할것을 권장합니다.
  • See Nrf2 (A-10): sc-365949 for additional antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • 현재 Nrf2 항체(437C2a)에 대해 선호하는 2차 검출 시약의 식별을 아직 완료하지 못했습니다. 이 작업은 진행 중입니다.

빠른 링크

더보기

NF-E2 DNA 결합 단백질은 p45와 MafK라는 두 개의 서브유닛으로 구성됩니다. 이 단백질은 마프 인식 요소(마프)와의 상호작용을 통해 발달 중인 적혈구 세포에서 글로빈 유전자의 발현을 조절합니다. 캡 앤 칼라(CNC) 계열로 통칭되는 NF-E2 관련 단백질은 Nrf1(TCF11이라고도 함), Nrf2 및 Nrf3을 포함하며, Maf 단백질과 이합체화하여 마레 서열과 결합하는 bZIP 전사인자입니다. Nrf 단백질은 또한 항산화 반응 요소(ARE)와 결합하며 해독 효소 및 산화 스트레스 반응의 조절에 관여합니다. 이들은 Jun 계열(c-Jun, Jun B 및 Jun D)과 이합체화하여 유전자 발현, 특히 해독 효소인 NQO1을 활성화합니다. Nrf2는 광범위하게 발현되며, 억제 단백질인 Keap1에서 방출을 자극하는 이종 생물체 및 항산화제로 처리한 후 핵으로 이동하는 것으로 생각됩니다.

연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.

주문정보

제품명카탈로그 번호 단위가격수량관심품목

Nrf2 항체 (437C2a)

sc-81342
100 µg/ml
$333.00

At which band is Nrf2 supposed to appear? is it 40KD (according to the figure) or 61KD (according to the molecular weight)??

Asked by: Khal24
Thank you for your question. The Western blot data published at 40 kDa with this antibody is of a human recombinant Nrf2 fusion protein and is not indicative of the endogenous molecular weight of Nrf2. Please see a useful reference for the molecular weight of Nrf2 below. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503463/
Answered by: Technical Support
Date published: 2019-02-10

I am using Nrf2 (437C2a): sc-81342 antibody for immunoprecipitation, how much antibody should I use?

Asked by: TinTin
Thank you for your question. We recommend using 1–10 µl (i.e., 0.2–2 µg) of antibody with 1 ml of cell lysate. However, optimal antibody concentration should be determined by titration. Please find our full immunoprecipitation protocol here: https://www.scbt.com/scbt/resources/protocols/immunoprecipitation-western-blots
Answered by: Technical Support
Date published: 2017-03-24
  • y_2025, m_9, d_5, h_6CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_ko_KR, sid_81342, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 111ms
  • QUESTIONS, PRODUCT
Rated 2 out of 5 by from ConfusingIts not showing the band at the correct molecular weight
Date published: 2018-03-07
Rated 2 out of 5 by from Bandas inespecíficasProbé el anticuerpo Nrf2 437C2a en un WB con la línea celular HEPG2,al mismo tiempo que el anticuerpo Nrf2 (A-10): sc-365949. Con el 437C2a aparecen muchas bandas inespecíficas, es mejor el A-10
Date published: 2018-02-22
Rated 5 out of 5 by from Beautiful strong single bandOur laboratory got this in replacement of the old ab we had. Glad we got this, did it once and didn't have to repeat the experiment.
Date published: 2017-11-12
Rated 5 out of 5 by from Reliable resultReliable result by western blot detect Nrf2 ,I suggest dilution 1:800,strong band wasdeteced at 40kda, I suggest use positive control for detection.
Date published: 2017-09-09
Rated 5 out of 5 by from very good antibody for human samplesThis is a very good antibody for human samples, and we will use it for human applications.
Date published: 2017-02-12
Rated 5 out of 5 by from 1:1000 for best resultsFor best results dilute primary antibody 1:1000 and secondary antibody 1:5000 and incubate for just 1 hour with each.
Date published: 2017-02-12
Rated 5 out of 5 by from GreatThis production is very great with high quanlity and high specificity.
Date published: 2016-11-19
Rated 3 out of 5 by from Strong band in WB with human recombinantStrong band in WB with human recombinant Nrf2 fusion protein. -SCBT QC
Date published: 2014-11-02
  • y_2025, m_9, d_5, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_8
  • loc_ko_KR, sid_81342, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 18ms
  • REVIEWS, PRODUCT
Nrf2 항체 (437C2a) is rated 4.0 out of 5 by 8.
  • y_2025, m_9, d_5, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_8
  • loc_ko_KR, sid_81342, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 105ms
  • REVIEWS, PRODUCT