LSm8 Antibody (2527C6a): sc-81315
- LSm8 Antibody (2527C6a) is a mouse monoclonal IgG1, cited in 2 publications, provided at 100 µg/ml
- raised against a recombinant protein corresponding to the C-terminal region of LSm8 of human origin
- recommended for detection of LSm8 of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for LSm8 Antibody (2527C6a). This work is in progress.
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LSm8 Antibody (2527C6a) is a mouse monoclonal IgG1 antibody that detects LSm8 in human samples through applications such as western blotting (WB) and immunoprecipitation (IP). LSm8, also known as YJR022W, is a crucial member of the snRNP Sm protein family, forming part of the LSm2-8 complex that is integral to RNA metabolism. This complex is essential for the processing of various non-coding RNAs, including pre-snoRNAs, pre-tRNAs, and pre-rRNAs, as well as the turnover of pre-mRNAs, highlighting LSm8′s importance in gene expression regulation. LSm8 is localized in the nucleus, where LSm8 specifically binds to the 3′-terminal U-tract of U6 snRNA, facilitating nuclear localization and ensuring proper assembly of the spliceosome. LSm8′s interaction with U6 snRNA is vital for the splicing process, which is critical for the maturation of mRNA and the overall regulation of gene expression. Anti-LSm8 antibody (2527C6a) enables researchers to gain insights into the dynamics of RNA processing and the functional roles of LSm proteins in cellular processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LSm8 Antibody (2527C6a) | sc-81315 | 100 µg/ml | $339.00 |