Headpin Antibody (B-5): sc-393882
- Headpin Antibody (B-5) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 260-287 within an internal region of Headpin of rat origin
- recommended for detection of Headpin of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Headpin Antibody (B-5) for WB applications. These reagents are now offered in bundles with Headpin Antibody (B-5) (see ordering information below).
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Headpin Antibody (B-5) is a mouse monoclonal IgG2a light chain antibody that detects Headpin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Headpin, also known as hurpin or serpinB13, is a skin-specific serine proteinase inhibitor that plays a crucial role in regulating proteolytic activity in the epidermis, which is essential for maintaining skin homeostasis and protecting against environmental stressors, including UV radiation. anti-Headpin antibody (B-5) is predominantly expressed in human keratinocytes, particularly in the HaCaT cell line and in lesional keratinocytes from psoriatic skin, highlighting its significance in skin health and disease. Notably, Headpin downregulation has been observed in squamous cell carcinoma of the oral cavity and in related cell lines, suggesting its potential role as a biomarker for skin malignancies. Headpin (B-5) antibody effectively detects this protein across various species and applications, making anti-Headpin antibody (B-5) an invaluable tool for researchers studying skin biology and related pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Headpin Antibody (B-5) | sc-393882 | 200 µg/ml | $322.00 | |||
Headpin Antibody (B-5): m-IgG Fc BP-HRP Bundle | sc-538329 | 200 µg Ab; 10 µg BP | $361.00 | |||
Headpin Antibody (B-5): m-IgGκ BP-HRP Bundle | sc-535916 | 200 µg Ab; 40 µg BP | $361.00 | |||
Headpin Antibody (B-5): m-IgG2a BP-HRP Bundle | sc-548271 | 200 µg Ab; 10 µg BP | $361.00 | |||
Headpin (B-5) Neutralizing Peptide | sc-393882 P | 100 µg/0.5 ml | $69.00 |