Date published: 2025-9-6

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FOXE3 항체 (D-6): sc-377465

4.5(2)
리뷰 쓰기질문하기

데이터 시트
  • FOXE3 항체(D-6) 는 마우스 monoclonal IgG1κ, 3간행물에 인용, 이며 200 µg/ml으로 제공합니다.
  • mouse origin의 FOXE3을 항원으로 사용하였습니다.
  • WB, IP, IF와 ELISA으로 mouse, rat와 human origin의 FOXE3을 검출할것을 권장합니다.
  • ChIP 에 사용하는 TransCruz시약(sc-377465 X, 200 µg/0.1 ml)이 있습니다.
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP 는 FOXE3 항체 (D-6) for WB applications. 이 시약은 이제 FOXE3 항체 (D-6)와 함께 번들로 제공됩니다(아래 주문 정보 참조).

빠른 링크

더보기

인간 포크헤드박스(FOX) 유전자군은 288아미노산 단백질인 FOXE3를 포함하여 최소 43개의 유전자로 구성되어 있습니다. FOXE3는 수정체 발달의 초기 단계와 수정체 소포가 닫히는 과정에서 중요한 역할을 하는 날개나선 전사인자입니다. FOXE3는 수정체 상피의 분화를 방지하면서 생존과 증식을 촉진하는 인자로도 작용할 수 있습니다. 수정체 섬유의 후방 세포가 분화하기 시작하면 FOXE3의 발현은 수정체의 전방 표면을 덮고 있는 미분화 세포로 제한됩니다. 선천성 원발성 약시(CPA)는 FOXE3 유전자의 결손 돌연변이로 인해 발생하는 희귀 발달 장애로 수정체가 없는 것으로 확인됩니다. CPA의 발달은 일반적으로 인간 배아 발생 4주 또는 5주째에 자극을 받습니다.

연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.

주문정보

제품명카탈로그 번호 단위가격수량관심품목

FOXE3 항체 (D-6)

sc-377465
200 µg/ml
$316.00

FOXE3 (D-6): m-IgG Fc BP-HRP 번들

sc-540723
200 µg Ab; 10 µg BP
$354.00

FOXE3 (D-6): m-IgG1 BP-HRP 번들

sc-542325
200 µg Ab; 20 µg BP
$354.00

FOXE3 항체 (D-6) X

sc-377465 X
200 µg/0.1 ml
$316.00

Why does the blot show two different bands or could you precise what does each band correspond to ?

Asked by: Cangee
Thank you for your question. The western blot image shows cell lysates that were transfected with a truncated peptide corresponding to the antibody's binding site. Endogenous FOXE3 will produce a signal at 33 kDa in western blots.
Answered by: Tech Support Europe
Date published: 2022-03-31

Why does the blot show two bands, and neither of which is at 33 kDa (which is the predicted protein size for human FOXE3 protein)?

Asked by: SPadula
Thank you for your question. The Western blot data may not be representative of the endogenous molecular weight for FOXE3. This is detected in a human FOXE3 transfected 293T lysate. The observed molecular weight of FOXE3 may be higher than the predicted molecular weight as a result of post-translational modifications of the protein.
Answered by: Technical Support
Date published: 2022-03-31

I need to use an antibody to detect the protein in samples of avian origin. Do you know if sc-377465: FOXE3 (D-6) mouse monoclonal antibody will work?

Asked by: jenniferc
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support
Date published: 2017-03-06
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Rated 4 out of 5 by from Hard to set, but works fineWe bought this product for a western blot on mouse lens epithelium. It took some time to find the right parameters to run the experiment, but when we found them, the antibody worked fine for our samples, and allowed quantification of FOXE3. The only problem remains the aspecific band at 50kDa, it would be interesting to understand what it corresponds to (obviously not FOXE3).
Date published: 2023-08-21
Rated 5 out of 5 by from Works well in WB in mouse FOXP1 transfectedWorks well in WB in mouse FOXP1 transfected 293T whole cell lysate. -SCBT QC
Date published: 2014-09-30
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FOXE3 항체 (D-6) is rated 4.5 out of 5 by 2.
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