EGF/FGF/PDGF receptor tyrosine kinase inhibitor 억제제 (CAS 1135256-66-4)

건강 상태 :

Solid

용해도 :

Soluble in DMSO (25 mg/ml), and ethanol (1 mg/ml).

저장 :

Store at 4° C

녹는점 :

256.77° C (Predicted)

비등점 :

594.56° C (Predicted)

밀도 :

~1.4 g/cm³ (Predicted)

굴절률 :

n²⁰_D 1.69 (Predicted)

IC50 :

Flg: IC₅₀ = 0.15 µM (human); PDGFR-β: IC₅₀ = 0.18 µM (human); Platelet-derived growth factor receptor : IC₅₀ = 0.63 µM (rat); c-Src: IC₅₀ = 1.76 µM (human); EGFR: IC₅₀ = 5.47 µM (human)

pK 값 :

pK_a: 9.85 (Predicted), pK_b: 2.59 (Predicted)

PubChem CID :

SMILES :

CC(C)(C)NC(=O)NC1=C(C=C2C=NC(=NC2=N1)N)C3=C(C=CC=C3Cl)Cl