DSCD75 Antibody (A-8): sc-374256

DSCD75 Antibody (A-8) is a mouse monoclonal IgG3 kappa light chain antibody that detects DSCD75 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). DSCD75 (A-8) antibody is available as the non-conjugated form. DSCD75, also known as UPF0670 protein C8orf55, is a 208 amino acid secreted protein that plays a crucial role in regulating mesenchymal stem cell functions, which are vital for tissue repair and regeneration. DSCD75 is primarily located in extracellular space, where DSCD75 can influence cell signaling pathways and interactions with other cells, thereby impacting processes such as differentiation and migration. The gene encoding DSCD75 is situated on human chromosome 8, a region associated with various diseases, including schizophrenia and certain types of cancer, highlighting the importance of understanding DSCD75 function and interactions. Using anti-DSCD75 antibody (A-8) in research can provide insights into biological mechanisms underlying these conditions and explore potential therapeutic targets.

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DSCD75 Antibody (A-8) References:

1. Preferential expression of an intact WRN gene in Werner syndrome cell lines in which a normal chromosome 8 has been introduced.  |  Kashino, G., et al. 2001. Biochem Biophys Res Commun. 289: 111-5. PMID: 11708785
2. Cytogenetic mapping of a novel locus for type II Waardenburg syndrome.  |  Selicorni, A., et al. 2002. Hum Genet. 110: 64-7. PMID: 11810298
3. Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q.  |  McQueen, MB., et al. 2005. Am J Hum Genet. 77: 582-95. PMID: 16175504
4. Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer.  |  Agrelo, R., et al. 2006. Proc Natl Acad Sci U S A. 103: 8822-7. PMID: 16723399
5. Non-Hodgkin's lymphomas with Burkitt-like cells are associated with c-Myc amplification and poor prognosis.  |  Mossafa, H., et al. 2006. Leuk Lymphoma. 47: 1885-93. PMID: 17065002
6. Initial characterization of the human central proteome.  |  Burkard, TR., et al. 2011. BMC Syst Biol. 5: 17. PMID: 21269460

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-DSCD75 Antibody (A-8) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-DSCD75 Antibody (A-8) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

DSCD75 Antibody (A-8) Specifications

Alternate Product Name: DSCD75

Product Clone Name: A-8

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₃ kappa light chain

Amino Acids: 55-85

Epitope Target: DSCD75

Epitope Species: human

Product Reactivity/Detection: DSCD75

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₃ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for DSCD75 Antibody (A-8): P: Blocking Peptide