D-myo-Inositol-1,4,5,6-tetraphosphate, sodium salt CAS: 157542-47-7
MF: C6H12O18P4•4Na
MW: 588.0
An inositol implicated in signal transduction.

D-myo-Inositol-1,4,5,6-tetraphosphate, sodium salt (CAS 157542-47-7)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 124ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Alternate Names: Ins(1,4,5,6)-P4; 1,4,5,6-IP4
Application D-myo-Inositol-1,4,5,6-tetraphosphate, sodium salt is an inositol implicated in signal transduction
CAS 등록번호: 157542-47-7
분자량: 588.0
분자식: C6H12O18P44Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

D-myo-Inositol-1,4,5,6-tetraphosphate, sodium salt is one of several different inositol oligophosphate isomers implicated in signal transduction. Production of Ins(1,4,5,6)P4 by intestinal epithelial cells increases approximately 2-14 fold, following infection with Salmonella. Ins(1,4,5,6)P4 antagonizes epidermal growth factor (EGF) signalling through the phosphatidylinositol 3-kinase pathway. Ins(1,4,5,6)P3 is less potent than Ins(1,4,5)P3 at initiating Ca2+ release when injected into Xenopus oocytes.


References

1 Eckmann, L., Rudolf, M.T., Ptasznik, A., et al. D-myo-Inositol 1,4,5,6-tetrakisphosphate produced in human intestinal epithelial cells in response to salmonella invasion inhibits phosphoinositide 3-kinase signaling pathways. Proc Natl Acad Sci USA 94 14456-14460 (1997). 2 DeLisle, S., Radenberg, T., Wintermantel, M.R., et al. Second messenger specificity of the inositol trisphosphate receptor: Reappraisal based on novel inositol phosphates. Am J Physiol Cell Physiol 35 C429-C436 (1994).

Appearance :
Lyophilized powder
Physical State :
Solid
용해도 :
Soluble in water (≥50 mg/ml). Practically insoluble in organic solvents.
저장 :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
SMILES :
[Na+].[Na+].[Na+].[Na+].O[[email protected]]1[[email protected]@H](OP(=O)([O-])O)[[email protected]](OP(=O)([O-])O)[[email protected]@H](OP(=O)([O-])O)[[email protected]](OP(=O)([O-])O)[[email protected]]1O

SDS(MSDS)다운로드

분석증명서

PDF문서를 열람,
프린트와 코멘트를 작성하려면 Adobe Acrobat Reader가 필요합니다.

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 150ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 10ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

산타크루즈바이오테크놀러지는 생물의학연구에 필요한 제품을 개발하는 선구자입니다. Toll Free 1-800-457-3801로 연락주세요. Copyright © 2007-2020 Santa Cruz Biotechnology, Inc. 판권소유. "Santa Cruz Biotechnology", 와 Santa Cruz Biotechnology, Inc. 로고, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", 및 San Juan Ranch 로고, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz"와 "EZ Touch" 는 Santa Cruz Biotechnology, Inc의 등록된 상표입니다. 모든 상표는 각자 소유주의 소유입니다.