Cysteamine Hydrochloride CAS: 156-57-0
MF: C2H7NS•HCl
MW: 113.61
An antioxidant and an inhibitor of DMBA-induced tumors.

Cysteamine Hydrochloride (CAS 156-57-0)

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Alternate Names: Beta-mercaptoethylamine hydrochloride; Decarboxycystine HCl; 2-Aminoethanethiol HCl; Cystaran
Application Cysteamine Hydrochloride is an antioxidant and an inhibitor of DMBA-induced tumors
CAS 등록번호: 156-57-0
순도: ≥99%
분자량: 113.61
분자식: C2H7NS•HCl
추가 정보: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
* 참조분석증명서대량의 측정 데이터(함수량포함).

Cysteamine Hydrochloride is the salt formulation of the decarboxylated form of the amino acid cysteine. Clinically, cysteamine hydrochloride is used in the treatment of radiation sickness and disorders of cysteine excretion. Cysteamine cleaves the disulfide bond with cystine to produce molecules that can escape the metabolic defect in cystinosis and cystinuria. It is believed to inhibit DMBA-induced tumors


References

Tatsuta M, Iishi H, Baba M, Taniguchi H. International Journal of Cancer. 48:605-8 (1991). IP C, Ganther HE. arcinogenesis. 13:1167-70 (1992). Tatsuta M, Lishi H, Baba M, Taniguchi H. International Journal of Cancer. 44:1008-11 (1989).

Appearance :
Crystalline powder
Physical State :
Solid
용해도 :
Soluble in water (400 mg/ml at 20° C), ethanol, methanol, DMSO, and alcohol (very soluble ).
저장 :
Store at 4° C
녹는점 :
67-71° C
굴절률 :
n20D 1.49 (Predicted)
IC50 :
CEM-SS: EC5050 = 41.6 µM; CEM-SS: IC50 = 71 µM (human); Plasmodium falciparum: IC50 = 200 µM
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
WGK Germany :
3
RTECS :
KJ0200000
PubChem CID :
Merck Index :
14: 2779
MDL Number :
MFCD00012904
EC Number :
205-858-1
Beilstein Registry :
3590083
SMILES :
C(CS)N.Cl

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PMID: # 26860350  ACS Appl Mater Interfaces. 5804-12.

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