mouse origin의 Cyp4f13 of mouse origin and Cyp4f6 of rat origin에서 에 가까운270-287의 아미노산사이에 위치한 항원결정부와 특정결합합니다.
Cyp4f13 항체(G-5)는 WB, IP, IF and ELISA으로 CYP4F3 of human origin, Cyp4f13 of mouse origin and Cyp4f6 of rat origin 를 감지하는 데에 추천한다 .
IP를 위해 agarose ;WB, IHC(P) and ELISA를 위해 HRP ;또는 IF, IHC(P) and FCM를 위해 phycoerythrin or FITC 에 결합된 Anti-Cyp4f13 항체 (G-5)를 제공한다.
WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Cyp4f13 Antibody (G-5) for WB applications. These reagents are now offered in bundles with Cyp4f13 Antibody (G-5) (see ordering information below).
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Cytochrome P450 proteins are heme-thiolate monooxygenases that mediate NADPH-dependent electron transport and function to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Specifically, cytochrome P450s are responsible for metabolizing arachidonic acid to hydroxyeicosatetraenoic acid (a regulator of blood pressure) and epoxyeicosatrienoic acid (a molecule involved in signaling events). Cyp4f13, (cytochrome P450, family 4, subfamily f, polypeptide 13), also known as Cypf13 or 0610030I10Rik, is a 523 amino acid murine protein that is encoded by a gene located on mouse chromosome 17 B1. The human homolog to Cyp4f13 is CYP4F3 (cytochrome P450 family 4 subfamily F member 3), also known as CPF3, CYP4F, LTB4H. CYP4F3 is a 520 amino acid member of the cytochrome P450 superfamily of enzymes and exists as two alternatively spliced isoforms, CYP4F3A and CYP4F3B. CYP4F3 may be involved in leukotriene B4 degradation.
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