COPE Antibody (C-4): sc-133194

COPE Antibody (C-4) is a mouse monoclonal IgG2b antibody that detects COPE in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). COPE, or coatomer protein complex epsilon, plays a crucial role in the formation of COPI-coated vesicles, which are essential for retrograde transport from the Golgi apparatus back to the endoplasmic reticulum (ER) and for intra-Golgi transport. COPE is primarily located in the cytoplasm and is integral to maintaining cellular homeostasis by facilitating the recycling of proteins and lipids, thus ensuring that the ER and Golgi apparatus function efficiently. COPE (C-4) antibody specifically targets a protein vital for the secretion of proteins and the overall trafficking of membrane-bound proteins, which are critical for various cellular processes, including cell signaling and metabolism. COPE interacts with other coatomer proteins, such as α-COP and β′-COP, forming a heptameric coatomer complex that is essential for the assembly of COPI vesicles. Anti-COPE antibody (C-4) specifically targets this protein, making COPE (C-4) monoclonal antibody an invaluable tool for researchers studying vesicular transport mechanisms and their implications in cellular function and disease.

The preferred COPE antibody is COPE Antibody (A-4): sc-133195.