CK-689 (CAS 170930-46-8)
Alternate Names:
CK689 CK 689 N-[2-(1H-indol-3-yl)ethyl]-2-methoxyacetamide N-(2-INDOL-3-YLETHYL)-2-METHOXYETHANAMIDE SCHEMBL9116077
CAS Number:
170930-46-8
Molecular Weight:
232.28
Molecular Formula:
C13H16N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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CK-689 (CAS 170930-46-8) References
- Arp2/3 complex inhibitors adversely affect actin cytoskeleton remodeling in the cultured murine kidney collecting duct M-1 cells. | Ilatovskaya, DV., et al. 2013. Cell Tissue Res. 354: 783-92. PMID: 24036843
- Arp2/3 and VASP Are Essential for Fear Memory Formation in Lateral Amygdala. | Basu, S., et al. 2016. eNeuro. 3: PMID: 27957528
- Long-term memory is maintained by continuous activity of Arp2/3 in lateral amygdala. | Basu, S., et al. 2020. Neurobiol Learn Mem. 167: 107115. PMID: 31733301
- TDAExplore: Quantitative analysis of fluorescence microscopy images through topology-based machine learning. | Edwards, P., et al. 2021. Patterns (N Y). 2: 100367. PMID: 34820649
- Synthesis, Screening and Characterization of Novel Potent Arp2/3 Inhibitory Compounds Analogous to CK-666. | Fokin, AI., et al. 2022. Front Pharmacol. 13: 896994. PMID: 35707404
- Initial ciliary assembly in Chlamydomonas requires Arp2/3 complex-dependent endocytosis. | Bigge, BM., et al. 2023. Mol Biol Cell. 34: ar24. PMID: 36753382
- An actin filament branching surveillance system regulates cell cycle progression, cytokinesis and primary ciliogenesis. | Cao, M., et al. 2023. Nat Commun. 14: 1687. PMID: 36973243
- Polarized SCAR and the Arp2/3 complex regulate apical cortical remodeling in asymmetrically dividing neuroblasts. | Cazzagon, G., et al. 2023. iScience. 26: 107129. PMID: 37434695
- N-WASP-dependent branched actin polymerization attenuates B-cell receptor signaling by increasing the molecular density of receptor clusters. | Bhanja, A., et al. 2023. Elife. 12: PMID: 38085658
- Arp2/3 complex and the pentose phosphate pathway regulate late phases of neutrophil swarming. | Glaser, KM., et al. 2024. iScience. 27: 108656. PMID: 38205244
Inhibitor of:
INF2, L-Plastin, Las17, MYH4, Myosin, Myosin-XVA, and Tropomyosin 4.Activator of:
BC055107, and EG231836.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CK-689, 25 mg | sc-507371 | 25 mg | $312.00 |