Chlorthalidone (CAS 77-36-1)

건강 상태 :

Solid

용해도 :

Soluble in water (Partly miscible), DMSO (> 3mg/ml), and methanol (> 3 mg/ml).

저장 :

Store at -20° C

녹는점 :

217-221° C

비등점 :

559.84° C (Predicted)

밀도 :

1.60 g/cm³ (Predicted)

굴절률 :

n²⁰_D 1.69 (Predicted)

IC50 :

Carbonic anhydrase II: IC₅₀ = 677 nM (human)

Ki 데이타 :

Carbonic anhydrase VII: K_i= 2.8 nM (human); Carbonic anhydrase IX: K_i= 23 nM (human); Carbonic anhydrase XIII: K_i= 15 nM (mus musculus); Carbonic anhydrase XII: K_i= 4.5 nM (human); Carbonic anhydrase VB: K_i= 9 nM (human)

pK 값 :

pK_a: 9.57 (Predicted), pK_b: 4.43 (Predicted)

WGK 독일 :

2

RTECS :

DB1556000

PubChem CID :

Merck 색인 :

14: 2193

MDL 번호 :

MFCD00036257

EC 번호 :

201-022-5

Beilstein 기재 :

312295

SMILES :

NS(=O)(=O)C1=CC(=CC=C1Cl)C1(O)NC(=O)C2=CC=CC=C12