human origin의 CGNL1에서 에 가까운 770-957 아미노산을 항원으로 사용하였습니다.
안티-CGNL1 항체 (E-6)는 WB, IP, IF and ELISA으로 mouse, rat and human유래의 CGNL1 를 감지하는 데에 추천한다.
IP를 위해 agarose ;WB, IHC(P) and ELISA를 위해 HRP ;또는 IF, IHC(P) and FCM를 위해 phycoerythrin or FITC 에 결합된 Anti-CGNL1 항체 (E-6)를 제공한다.
WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CGNL1 Antibody (E-6) for WB applications. These reagents are now offered in bundles with CGNL1 Antibody (E-6) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
CGNL1 Antibody (E-6) is a high quality monoclonal CGNL1 antibody (also designated CGNL1 antibody) suitable for the detection of the CGNL1 protein of mouse, rat and human origin. CGNL1 Antibody (E-6) is available as both the non-conjugated anti-CGNL1 antibody form, as well as multiple conjugated forms of anti-CGNL1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Diffusion of solutes is prevented across certain barriers by the formation of tight junction seals. Occludin and Cingulin interact with other proteins to direct the formation and regulation of tight junctions. Cingulin, a protein component of the submembrane plaque of tight junctions (TJ), contains globular and coiled-coil domains and interacts in vitro with several TJ and cytoskeletal proteins, including the PDZ protein ZO-1. CGNL1 (cingulin-like 1), also known as JACOP (junction-associated coiled-coil protein), is a 1.302 amino acid tight junction protein belonging to the Cingulin family. Expressed in smooth muscle, spleen, testis, fetal brain, amygdala, corpus callosum, cerebellum, thalamus and subthalamic nucleus of adult brain. CGNL1 exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 15q21.3. CGNL1 may participate in anchoring the apical junctional complex, primarily tight junctions, to actin-based cytoskeletons. Mutations in the gene encoding CGNL1 are the cause of aromatase excess syndrome, which is characterized by an estrogen excess due to an increased aromatase activity.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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