Carprofen CAS: 53716-49-7
MF: C15H12ClNO2
MW: 273.71
An antiinflammatory inhibitor of COX-2.

Carprofen (CAS 53716-49-7)

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Carprofen is rated 5.0 out of 5 by 1.
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Alternate Names: Imadyl; Rimadyl; 6-Chloro-a-methyl-9H-carbazole-2-acetic acid
Application Carprofen is an antiinflammatory inhibitor of COX-2
CAS 등록번호: 53716-49-7
순도: ≥98%
분자량: 273.71
분자식: C15H12ClNO2
추가 정보: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
* 참조분석증명서대량의 측정 데이터(함수량포함).

Carprofen is a non-steroidal antiinflammatory compound whose mechanism of action is dependent upon inhibiting the production of COX-2 and other sources of prostaglandins


References

1. Mancini, J.A., et al. 1995. J. Biol. Chem. 270: 29372-72937. PMID: 749397
2. Greig, G.M., et al. 1997. Mol. Pharmacol. 52: 829-838. PMID: 9351974

Physical State :
Solid
용해도 :
Practically insoluble in water; Soluble in DMSO, methanol, and ethanol.
저장 :
Store at 4° C
녹는점 :
186-202° C
비등점 :
~509.1° C at 760 mmHg (Predicted)
밀도 :
~1.4 g/cm3 (Predicted)
굴절률 :
n20D 1.73 (Predicted)
IC50 :
Cox-2: IC50 = 100 nM (human); Cox-1: IC50 = 13.2 µM (human); Anandamide amidohydrolase: IC50 = 78.6 µM (rat)
pK Values :
pKa: 4.84 (Predicted)
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
WGK Germany :
3
RTECS :
FE3180000
PubChem CID :
Merck Index :
14: 1862
MDL Number :
MFCD00079028
EC Number :
258-712-4
Beilstein Registry :
487098
SMILES :
CC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)O

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