Molecular structure of BML-259, CAS Number: 267654-00-2
Molecular structure of BML-259, CAS Number: 267654-00-2
Molecular structure of BML-259, CAS Number: 267654-00-2
BML-259 (CAS 267654-00-2)
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Alternate Names:
N-(5-Isopropyl-2-thiazolyl)phenylacetamide
Application:
BML-259 is a potent inhibitor of CDK5 & CDK2/cyclin E
CAS Number:
267654-00-2
Purity:
>95%
Molecular Weight:
260.4
Molecular Formula:
C14H16N2OS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
BML-259 is a potent inhibitor of CDK5 (IC50 = 64 nM) and CDK2 / cyclin E (IC50 = 98 nM)
BML-259 (CAS 267654-00-2) References
Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer's disease: C.J. Helal, et al.; Bioorg. Med. Chem. Lett. 14, 5521 (2004)
Inhibitor of:
Cdk2, Cdk5, Rad9B, and Ser/Thr Protein Kinase.
Physical State :
Solid
Solubility :
30mg/ml soluble in DMSO or dimethyl formamide, 0.25mg/ml soluble in 100% ethanol
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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