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β lactamase Antibody (3E11.G3) is a mouse monoclonal IgG3 antibody that detects β-lactamase in Enterobacter cloacae through enzyme-linked immunosorbent assay (ELISA). β-lactamase (3E11.G3) antibody recognizes an enzyme produced by various bacteria that hydrolyzes the β-lactam ring of antibiotics, rendering them ineffective. This mechanism is particularly significant in clinical settings, where infections caused by β-lactamase-producing bacteria can lead to treatment failures and increased morbidity. β-lactamase monoclonal antibody (3E11.G3) helps monitor resistance to a wide range of β-lactam antibiotics, including penicillins and cephalosporins. Understanding β-lactamase structure is essential, as variations exist among different classes (A-D), with classes A, C, and D utilizing a serine-based mechanism, while class B, known as metallo-β-lactamase, requires zinc for activity. The diversity in structure and function among these classes underscores the need for specific detection methods, such as anti-β-lactamase antibody (3E11.G3), to effectively identify and study resistant bacterial strains.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
β lactamase Antibody (3E11.G3) | sc-66061 | 100 µg/ml | $322.00 |