Date published: 2025-9-9

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Alix 항체 (2H12): sc-53539

4.4(5)
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데이터 시트
  • Alix 항체(2H12) 는 마우스 monoclonal IgG1κ, 11간행물에 인용, 이며 200 µg/ml으로 제공합니다.
  • recommended for detection of by WB, IP, IF와 ELISA으로 mouse, rat, human와 Xenopus origin의 Alix을 검출할것을 권장합니다.
  • See Alix (1A12): sc-53540 for additional antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG Fc BP-HRP, 1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP는 Alix 항체(2H12) WB 애플리케이션용입니다. 이 시약은 이제 Alix 항체(2H12)와 함께 번들로 제공됩니다(아래 주문 정보 참조).

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프로그램된 세포 사멸 6 상호 작용 단백질(PDCD6 상호 작용 단백질)이라고도 하는 ALG-2 상호 작용 단백질(Alix)은 세포질 단백질입니다. 알릭스는 세포 사멸 관련 단백질(ALG-2 및 PDCD6) 및 세포 사멸 조절 인자인 CIN85와 상호 작용합니다. 또한, 알릭스는 수송에 필요한 소포체 분류 복합체(ESCRT) 단백질(Tsg101 및 CHMP4)과 상호 작용하며 HIV-1과 결합할 수 있습니다. 코팅 소포 형성의 초기 및 후기 단계에 필요한 막의 곡률을 변화시키는 효소인 엔도필린(SH3P4, SH3P8 및 SH3P13)도 알릭스와 결합합니다. 알릭스는 소포에 통합하기 위해 소포체의 화물 단백질을 농축하고 분류하는 데 관여합니다.

연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.

주문정보

제품명카탈로그 번호 단위가격수량관심품목

Alix 항체 (2H12)

sc-53539
200 µg/ml
$316.00

Alix (2H12): m-IgG Fc BP-HRP 번들

sc-536983
200 µg Ab; 10 µg BP
$354.00

Alix (2H12): m-IgGκ BP-HRP 번들

sc-534162
200 µg Ab; 40 µg BP
$354.00

Alix (2H12): m-IgG1 BP-HRP 번들

sc-544939
200 µg Ab; 20 µg BP
$354.00

Are there any issues with using sc-53539: Alix (2H12) mouse monoclonal primary antibody on mouse samples?

Asked by: Germaine
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-53539 conjugates.
Answered by: Technical Support
Date published: 2017-03-07

What is the lower mw band with the nuclear extract.   Is that an Alix isoform or contaminate ?

Asked by: Roger Madison
Thank you for your question. We have not further characterized the lower molecular weight band observed in the nuclear extracts tested (HeLa, Jurkat, K-562, THP-1 and U-937) by Western blot with this Alix Antibody (2H12): sc-53539. However, this band is also observed with a different Alix antibody with a different epitope, sc-53540: Alix (1A12).
Answered by: Technical Support
Date published: 2016-12-20
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Rated 5 out of 5 by from Good antibody for WBThe Alix Antibody (2H12): sc-53539 works well for Western blot applications. This antibody has also been cited several times for further verification.
Date published: 2017-01-18
Rated 4 out of 5 by from Worked with transfected lysate by WBWorked with transfected lysate by WB -SCBT QC
Date published: 2015-04-28
Rated 4 out of 5 by from Publishable data in WB using mouse brainPublishable data in WB using mouse brain tumor exosomes -SCBT Publication Review
Date published: 2015-03-14
Rated 5 out of 5 by from Bands seen in WB using HeLaBands seen in WB using HeLa, Jurkat, K-562, THP-1 and U-937 nuclear extracts. -SCBT QC
Date published: 2015-01-10
Rated 4 out of 5 by from Publishable data in IP using mouse C2C12(myoblastPublishable data in IP using mouse C2C12(myoblast cell line) -SCBT Publication Review
Date published: 2013-01-24
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Alix 항체 (2H12) is rated 4.4 out of 5 by 5.
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