AKAP 95 Antibody (47): sc-135828
- AKAP 95 Antibody (47) is a mouse monoclonal IgG2b provided at 50 µg/0.5 ml
- raised against amino acids 460-781 of AKAP 95 of human origin
- recommended for detection of AKAP 95 of human origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for AKAP 95 Antibody (47). This work is in progress.
AKAP 95 Antibody (47) is a mouse monoclonal IgG2b antibody that detects AKAP 95 in human samples through western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF) applications. AKAP 95, also known as AKAP 8, is a crucial nuclear matrix protein predominantly expressed in vital organs such as the liver, heart, pancreas, kidney, and skeletal muscle. Anti-AKAP 95 antibody (47) enables research into PKA signaling compartmentalization, which is essential for maintaining specific localization within the cell. This localization is achieved through the interaction of the R subunit (RII) of PKA with A-kinase anchoring proteins (AKAPs), including AKAP 95. During mitosis, AKAP 95 is recruited to chromosomes, playing a pivotal role in mitotic progression. Furthermore, AKAP 95 forms a complex with HA95 and histone deacetylase 3 (HDAC3), which is necessary for the deacetylation of Histone H3 during mitosis, highlighting its importance in regulating gene expression and chromatin dynamics. AKAP 95 (47) monoclonal antibody serves as an invaluable tool for researchers studying PKA signaling pathways and their implications in cellular processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AKAP 95 Antibody (47) | sc-135828 | 50 µg/0.5 ml | $322.00 |