AK1 Antibody (G-5): sc-165981
- AK1 Antibody (G-5) is a mouse monoclonal IgG2a κ, cited in 3 publications, provided at 200 µg/ml
- raised against amino acids 105-194 mapping at the C-terminus of AK1 of human origin
- recommended for detection of AK1 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for AK1 Antibody (G-5) for WB applications. These reagents are now offered in bundles with AK1 Antibody (G-5) (see ordering information below).
AK1 Antibody (G-5) is a mouse monoclonal IgG2a antibody that detects adenylate kinase 1 (AK1) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-AK1 antibody (G-5) plays a crucial role in cellular energy homeostasis by catalyzing the transfer of phosphate groups between adenine nucleotides, which are vital for various metabolic processes. AK1 (G-5) antibody is predominantly located in the cytosol of skeletal muscle, brain, and erythrocytes, where AK1 is often found clustered within myofibrils or associated with cellular membranes. This strategic localization is essential for AK1 function, as such positioning allows efficient regulation of energy supply necessary for muscle contraction and neuronal signaling. Deficiencies in AK1 can lead to significant metabolic disturbances, including hemolytic anemia due to impaired energy metabolism in erythrocytes. Using AK1 monoclonal antibody (G-5), researchers can gain insights into AK1′s role in energy regulation and implications in various physiological and pathological conditions.
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AK1 Antibody (G-5) References:
- Proteomic analysis of cervical cancer cells treated with adenovirus-mediated MDA-7. | Wei, L., et al. 2008. Cancer Biol Ther. 7: 510-6. PMID: 18299662
- Proteome-wide profiling of the MCF10AT breast cancer progression model. | Choong, LY., et al. 2010. PLoS One. 5: e11030. PMID: 20543960
- The many isoforms of human adenylate kinases. | Panayiotou, C., et al. 2014. Int J Biochem Cell Biol. 49: 75-83. PMID: 24495878
- MAPRE1 as a plasma biomarker for early-stage colorectal cancer and adenomas. | Taguchi, A., et al. 2015. Cancer Prev Res (Phila). 8: 1112-9. PMID: 26342024
- High expression of AK1 predicts inferior prognosis in acute myeloid leukemia patients undergoing chemotherapy. | Qin, T., et al. 2020. Biosci Rep. 40: PMID: 32519744
- Proteome activity landscapes of tumor cell lines determine drug responses. | Frejno, M., et al. 2020. Nat Commun. 11: 3639. PMID: 32686665
- Genome-wide analysis of mRNA and microRNA expression in colorectal cancer and adjacent normal mucosa. | Ito, Y., et al. 2022. J Pathol Clin Res. 8: 313-326. PMID: 35285580
- Colorectal polyps increase the glycolytic activity. | Rebane-Klemm, E., et al. 2023. Front Oncol. 13: 1171887. PMID: 37342183
- Comprehensive Urinary Proteome Profiling Analysis Identifies Diagnosis and Relapse Surveillance Biomarkers for Bladder Cancer. | Chang, Q., et al. 2024. J Proteome Res. 23: 2241-2252. PMID: 38787199
- Comprehensive multiomics analysis reveals distinct differences between pediatric choroid plexus papilloma and carcinoma. | Choi, Y., et al. 2024. Acta Neuropathol Commun. 12: 93. PMID: 38867333
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AK1 Antibody (G-5) | sc-165981 | 200 µg/ml | $322.00 | |||
AK1 Antibody (G-5): m-IgG Fc BP-HRP Bundle | sc-539976 | 200 µg Ab; 10 µg BP | $361.00 | |||
AK1 Antibody (G-5): m-IgG2a BP-HRP Bundle | sc-546827 | 200 µg Ab; 10 µg BP | $361.00 |